| Alternative name1 | LDLR Relative with 11 Ligand Binding Repeats, LR11, LRP9, Low Density Lipoprotein Receptor Relative with 11 Ligand Binding Repeats, Mosaic Protein LR11, SorLA-1, Sortilin-related R, gp250, Anti-SORL1 (Sortilin-related Receptor L(DLR class) A Repeats Containing |
| Alternative name2 | LDLR Relative with 11 Ligand Binding Repeats, LR11, LRP9, Low Density Lipoprotein Receptor Relative with 11 Ligand Binding Repeats, Mosaic Protein LR11, SorLA-1, Sortilin-related R, gp250, SORL1 (Sortilin-related Receptor L(DLR class) A Repeats Containing |
| Alternative name3 | LDLR Relative with 11 Ligand Binding Repeats, LR11, LRP9, Low Density Lipoprotein Receptor Relative with 11 Ligand Binding Repeats, Mosaic Protein LR11, SorLA-1, Sortilin-related R, gp250, SORL1 (Sortilin-related Receptor L(DLR class) A Repeats Containing |
| Alternative name4 | SORL1 |
| Alternative name5 | LDLR Relative with 11 Ligand Binding Repeats, LR11, LRP9, Low Density Lipoprotein Receptor Relative with 11 Ligand Binding Repeats, Mosaic Protein LR11, SorLA-1, Sortilin-related R, gp250, Anti -SORL1 (Sortilin-related Receptor L(DLR class) A Repeats Containing |
| Other names | L(DLR class) A repeats containing, L(DLR class) A repeats-containing, LDLR relative with 11 ligand-binding repeats, LDLR relative with 11 ligand-binding repeats, LR11, Low-density lipoprotein receptor relative with 11 ligand-binding repeats, SorLA-1, Sortilin-related receptor, Sorting protein-related receptor containing LDLR class A repeats, low-density lipoprotein receptor relative with 11 ligand-binding repeats, mosaic protein LR11, sortilin-related receptor, sortilin-related receptor, sortilin-related receptor, sorting protein-related receptor containing LDLR class A repeats, sortilin-related receptor preproprotein |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | C11orf32, C11orf32, LDLR relative with 11 ligand-binding repeats, LR11, LR11, LRP9, SORL1, SORLA, SorLA, SorLA-1, gp250, SORL1 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Goat |
| Species reactivity | Mouse, Rabbit, Human |
| Specificity and cross-reactivity | Mouse (100% identity with immunogen) and Rabbit (100% identity with immunogen) due to sequence homology, Species Crossreactivity: Expected to crossreact with Human (100% identity with immunogen) |
| Purification method | Affinity Purified by immunoaffinity chromatography |
| Form/Appearance | 0, pH 7, 2, 5% BSA, Supplied as a liquid in TBS |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile glycerol (40-50%), aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB), ELISA (EL/EIA) |
| Description | Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target | LDLR Relative with 11 Ligand Binding Repeats, LR11, LRP9, Lipoprotein Receptor Relative with 11 Ligand Binding Repeats, Mosaic Protein LR11, SorLA-1, Sortilin-related R, SORL1 (Sortilin-related Receptor L(DLR class) A Repeats gp250 |
| Short name | LDLR Relative with 11 Ligand Binding Repeats, LR11, LRP9, Low Density Lipoprotein Receptor Relative with 11 Ligand Binding Repeats, Mosaic Protein LR11, SorLA-1, Sortilin-related R, SORL1 (Sortilin-related Receptor L(DLR class) A Repeats gp250 |
| Alternative name | L(DLR class) A repeats containing (Sortilin-related Receptor L(DLR class) A Repeats Containing, LR11, LRP9, Low Density Lipoprotein Receptor Relative including 11 Ligand Binding Repeats, Mosaic Protein LR11, SorLA-1, Sortilin-related R, gp250, low density lipoprotein receptor Relative including 11 Ligand Binding Repeats, sortilin-related receptor |
| Alternative to gene target | ADP-ribosylation factor binding, C11orf32 and gp250 and LR11 and LRP9 and SORLA and SorLA-1, Cell surfaces, FH and FHC and LDLCQ2, L(DLR class) A repeats containing, LDLR and IDBG-28808 and ENSG00000130164 and 3949, LDLR and IDBG-643476 and ENSBTAG00000012314 and 281276, Ldlr and IDBG-141358 and ENSMUSG00000032193 and 16835, SORL1 and IDBG-632166 and ENSBTAG00000014611 and 533166, SORL1 and IDBG-74757 and ENSG00000137642 and 6653, Sorl1 and IDBG-154026 and ENSMUSG00000049313 and 20660, nuclei, sortilin-related receptor, this GO :0000042 and protein targeting to this GO lgi and biological process this GO :0001540 and beta-amyloid binding and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005641 and nuclear envelope lumen and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005771 and multivesicular body and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006605 and protein targeting and biological process this GO :0006622 and protein targeting to lysosome and biological process this GO :0006869 and lipid transport and biological process this GO :0006892 and post- this GO lgi vesicle-mediated transport and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007165 and signal transduction and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008219 and cell death and biological process this GO :0008283 and cell proliferation and biological process this GO :0014910 and regulation of smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030306 and ADP-ribosylation factor binding and molecular function this GO :0031985 and this GO lgi cisterna and cellular component this GO :0032091 and negative regulation of protein binding and biological process this GO :0032460 and negative regulation of protein oli this GO merization and biological process this GO :0034362 and low-density lipoprotein particle and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0045053 and protein retention in this GO lgi apparatus and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0050768 and negative regulation of neurogenesis and biological process this GO :0051604 and protein maturation and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070863 and positive regulation of protein exit from endoplasmic reticulum and biological process this GO :1901215 and negative regulation of neuron death and biological process this GO :1902430 and negative regulation of beta-amyloid formation and biological process this GO :1902771 and positive regulation of choline O-acetyltransferase activity and biological process this GO :1902948 and negative regulation of tau-protein kinase activity and biological process this GO :1902953 and positive regulation of ER to this GO lgi vesicle-mediated transport and biological process this GO :1902955 and positive regulation of early endosome to recycling endosome transport and biological process this GO :1902960 and negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process and biological process this GO :1902963 and negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process and biological process this GO :1902966 and positive regulation of protein localization to early endosome and biological process this GO :1902997 and negative regulation of neurofibrillary tangle assembly and biological process this GO :2001137 and positive regulation of endocytic recycling and biological process, this GO :0001523 and retinoid metabolic process and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0005041 and low-density lipoprotein receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005905 and coated pit and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006897 and endocytosis and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007603 and phototransduction, this GO :0001540: beta-amyloid binding, this GO :0001540: beta-amyloid binding and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding and also this GO :0030169: low-density lipoprotein particle binding and also this GO :0030306: ADP-ribosylation factor binding, this GO :0001948: glycoprotein binding, this GO :0001948: glycoprotein binding and also this GO :0005041: low-density lipoprotein receptor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0030169: low-density lipoprotein particle binding and also this GO :0030229: very-low-density lipoprotein particle receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005041: low-density lipoprotein receptor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0030169: low-density lipoprotein particle binding, this GO :0030169: low-density lipoprotein particle binding, this GO :0030229: very-low-density lipoprotein particle receptor activity, this GO :0030306: ADP-ribosylation factor binding, very-low-density lipoprotein particle receptor activity, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0010867 and positive regulation of triglyceride biosynthetic process and biological process this GO :0010899 and regulation of phosphatidylcholine catabolic process and biological process this GO :0015914 and phospholipid transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030229 and very-low-density lipoprotein particle receptor activity and molecular function this GO :0030299 and intestinal cholesterol absorption and biological process this GO :0030301 and cholesterol transport and biological process this GO :0030669 and clathrin-coated endocytic vesicle membrane and cellular component this GO :0034362 and low-density lipoprotein particle and cellular component this GO :0034383 and low-density lipoprotein particle clearance and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042159 and lipoprotein catabolic process and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0043235 and receptor complex and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0070508 and cholesterol import and biological process this GO :2000188 and regulation of cholesterol homeostasis and biological process, low density lipoprotein receptor |
| Identity | 11185 |
| Gene | SORL1 |
| Long gene name | sortilin related receptor 1 |
| Synonyms gene | C11orf32 |
| Synonyms gene name | L(DLR class) A repeats-containing , chromosome 11 open reading frame 32 sortilin-related receptor |
| Synonyms | gp250 LR11 LRP9 SorLA SorLA-1 |
| Synonyms name | LDLR relative with 11 ligand-binding repeats |
| Locus | 11q24, 1 |
| Discovery year | 1996-12-27 |
| GenBank acession | Y08110 |
| Entrez gene record | 6653 |
| Pubmed identfication | 9157966 8940146 |
| RefSeq identity | NM_003105 |
| Classification | Fibronectin type III domain containing |
| Havana BLAST/BLAT | OTTHUMG00000166057 |
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