Name : Sox17 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN1339305820
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Sox17 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the Sox17 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This Sox17 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q61473 |
| Purity | Antigen affinity |
| Description | Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3', Inhibits Wnt signaling, Isoform 2 (T-SOX17) shows no DNA-binding activity, Modulates transcriptional regulation via WNT3A, Plays a key role in the regulation of embryonic development, Probable transcriptional activator in the premeiotic germ cells, Promotes degradation of activated CTNNB1, Required for normal development of the definitive gut endoderm, Required for normal looping of the embryonic heart tube, Acts as transcription regulator that binds target promoter DNA and bends the DNA |
| Immunogen | This Sox17 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of mouse Sox17 |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Sox17 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Sox17 |
| Short name | Sox17 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Sox17 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 18122 |
| Gene | SOX17 |
| Long gene name | SRY-box 17 |
| Synonyms gene name | SRY (sex determining region Y)-box 17 SRY box 17 |
| Locus | 8q11, 23 |
| Discovery year | 2002-02-15 |
| GenBank acession | AB073988 |
| Entrez gene record | 64321 |
| Pubmed identfication | 11786926 |
| Classification | SRY-boxes |
| Havana BLAST/BLAT | OTTHUMG00000164377 |