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Sox17 Antibody

Sox17 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSox17
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the Sox17 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Sox17 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q61473
PurityAntigen affinity
Description Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3', Inhibits Wnt signaling, Isoform 2 (T-SOX17) shows no DNA-binding activity, Modulates transcriptional regulation via WNT3A, Plays a key role in the regulation of embryonic development, Probable transcriptional activator in the premeiotic germ cells, Promotes degradation of activated CTNNB1, Required for normal development of the definitive gut endoderm, Required for normal looping of the embryonic heart tube, Acts as transcription regulator that binds target promoter DNA and bends the DNA
ImmunogenThis Sox17 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of mouse Sox17
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Sox17 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSox17
Short nameSox17 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSox17 (Antibody to)
Alternative techniqueantibodies
Identity 18122
Gene SOX17
Long gene name SRY-box 17
Synonyms gene name SRY (sex determining region Y)-box 17 SRY box 17
Locus 8q11, 23
Discovery year 2002-02-15
GenBank acession AB073988
Entrez gene record 64321
Pubmed identfication 11786926
Classification SRY-boxes
Havana BLAST/BLAT OTTHUMG00000164377

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