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SP1 Antibody

SP1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSP1 Primary Polyclonal Antibody
Also known asSP1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSP1
SpecificityThis is a highly specific antibody against SP1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range700-750/785
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TSFP1/SP1
Gene ID number6667
Swiss ProtP08047
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds also the PDGFR-alpha G-box promoter, Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, Highly regulated by post-translational modifications (phosphorylations, Implicated in chromatin remodeling, In complex with ATF7IP, Isoform 3 is a stronger activator of transcription than isoform 1, May have a role in modulating the cellular response to DNA damage, Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter, Plays an essential role in the regulation of FE65 gene expression, Positively regulates the transcription of the core clock component ARNTL/BMAL1, apoptosis, differentiation and immune responses, glycosylation and acetylation), maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression, proteolytic cleavage, sumoylation, Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names SP1, TSFP1, Transcription factor Sp1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSP1
Short nameSP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSP1 (Antibody to)
Alternative techniqueantibodies
Identity 11205
Gene SP1
Long gene name Sp1 transcription factor
Synonyms name specificity protein 1
Locus 12q13, 13
Discovery year 1991-06-04
GenBank acession J03133
Entrez gene record 6667
Pubmed identfication 1662663
Classification Sp transcription factors Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000170047

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