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SP1 Antibody, FITC Conjugated

SP1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, SP1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSP1
SpecificityThis is a highly specific antibody against SP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range700-750/785
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human TSFP1/SP1
Gene ID number6667
Swiss ProtP08047
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds also the PDGFR-alpha G-box promoter, Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, Highly regulated by post-translational modifications (phosphorylations, Implicated in chromatin remodeling, In complex with ATF7IP, Isoform 3 is a stronger activator of transcription than isoform 1, May have a role in modulating the cellular response to DNA damage, Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter, Plays an essential role in the regulation of FE65 gene expression, Positively regulates the transcription of the core clock component ARNTL/BMAL1, apoptosis, differentiation and immune responses, glycosylation and acetylation), maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression, proteolytic cleavage, sumoylation, Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSP1 Conjugated
Short name FITC Conjugated, SP1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, SP1 (Antibody to)
Alternative techniqueantibodies
Identity 11205
Gene SP1
Long gene name Sp1 transcription factor
Synonyms name specificity protein 1
Locus 12q13, 13
Discovery year 1991-06-04
GenBank acession J03133
Entrez gene record 6667
Pubmed identfication 1662663
Classification Sp transcription factors Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000170047

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