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SPAG5 Antibody

SPAG5 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSPAG5 Primary Polyclonal Antibody
Also known asSPAG5 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSPAG5
SpecificityThis is a highly specific antibody against SPAG5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1120-1170/1193
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPAG5/MAP126
Gene ID number10615
Swiss ProtQ96R06
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In complex with SKAP, In non-mitotic cells, May contribute to the regulation of separase activity, May enhance GSK3B-mediated phosphorylation of other substrates, May regulate AURKA localization to mitotic spindle, Required for chromosome alignment, and maintenance of spindle pole architecture, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), normal timing of sister chromatid segregation, promotes stable microtubule-kinetochore attachments, such as MAPT/TAU, thereby preventing mTORC1 hyperactivation-induced apoptosis, upon stress induction, Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Astrin, DEEPEST, Mitotic spindle-associated protein p126, SPAG5, Sperm-associated antigen 5, hMAP126, MAP126
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSPAG5
Short nameSPAG5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSPAG5 (Antibody to)
Alternative techniqueantibodies
Identity 13452
Gene SPAG5
Long gene name sperm associated antigen 5
Synonyms DEEPEST MAP126 hMAP126
Synonyms name mitotic spindle coiled-coil related protein astrin mitotic spindle associated protein p126
Locus 17q11, 2
Discovery year 2002-10-08
GenBank acession AF063308
Entrez gene record 10615
Pubmed identfication 11549262
RefSeq identity NM_006461
Havana BLAST/BLAT OTTHUMG00000166586

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