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Specificity Protein 1 Antibody (SP1)

Specificity Protein 1 Antibody (SP1) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSpecificity Protein 1 (SP1)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the SP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis SP1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P08047
PurityAntigen affinity
Description Binds also the PDGFR-alpha G-box promoter, Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, Highly regulated by post-translational modifications (phosphorylations, Implicated in chromatin remodeling, May have a role in modulating the cellular response to DNA damage, Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter, Plays an essential role in the regulation of FE65 gene expression, [UniProt], apoptosis, differentiation and immune responses, glycosylation and acetylation), proteolytic cleavage, sumoylation, Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli
ImmunogenA portion of amino acids 677-707 from the human protein was used as the immunogen for this SP1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SP1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetProtein 1 (SP1)
Short nameProtein 1 Antibody (SP1)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSpecificity Protein 1 (Antibody to) (SP1)
Alternative techniqueantibodies
Identity 11205
Gene SP1
Long gene name Sp1 transcription factor
Synonyms name specificity protein 1
Locus 12q13, 13
Discovery year 1991-06-04
GenBank acession J03133
Entrez gene record 6667
Pubmed identfication 1662663
Classification Sp transcription factors Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000170047

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