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SPG21 Antibody, Biotin Conjugated

SPG21 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, SPG21 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSPG21
SpecificityThis is a highly specific antibody against SPG21
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human SPG21
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Belonging to the AB hydrolase superfamily, Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network, The gene encoding Maspardin is encoded by human chromosome 15, an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs, which houses over 700 genes and comprises nearly 3% of the human genome, Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms ACP33 GL010 BM-019 MAST
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSPG21 Conjugated
Short name Conjugated, SPG21 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name Mast syndrome) (Antibody to), biotinilated coupled, spastic paraplegia 21 (autosomal recessive
Alternative techniqueantibodies
Alternative to gene target CD4 receptor binding, Mast syndrome), SPG21 and IDBG-16930 and ENSG00000090487 and 51324, SPG21 and IDBG-645311 and ENSBTAG00000011540 and 404069, Spg21 and IDBG-177905 and ENSMUSG00000032388 and 27965, nuclei, this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0008219 and cell death and biological process this GO :0010008 and endosome membrane and cellular component this GO :0030140 and trans- this GO lgi network transport vesicle and cellular component this GO :0042609 and CD4 receptor binding and molecular function this GO :0050851 and antigen receptor-mediated signaling pathway and biological process, this GO :0042609: CD4 receptor binding, this GO :0042609: CD4 receptor binding, spastic paraplegia 21 (autosomal recessive
Identity 20373
Gene SPG21
Long gene name SPG21, maspardin
Synonyms gene name Mast syndrome) , spastic paraplegia 21 (autosomal recessive
Locus 15q22, 31
Discovery year 2004-04-30
GenBank acession AF208861
Entrez gene record 51324
Pubmed identfication 11113139 14564668
RefSeq identity NM_016630
Havana BLAST/BLAT OTTHUMG00000133098

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