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Sphingomyelin Synthase 1 Antibody

Sphingomyelin Synthase 1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSphingomyelin Synthase 1 Antibody
Also known asSphingomyelin Synthase 1 Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSphingomyelin Synthase 1
SpecificityThis is a highly specific antibody against Sphingomyelin Synthase 1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range50-100/419
Subcellular locationIntracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sphingomyelin Synthase 1
Gene ID number259230
Swiss ProtQ86VZ5
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, Major form in macrophages, May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide, Required for cell growth in certain cell types such as HeLa cells, Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide, elevated temperature and exogenously supplied sphingolipids, on to the primary hydroxyl of ceramide, osmotic stress, phosphatidylcholine, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate, sphingomyelin, through transfer of the phosphatidyl head group, Sphingomyelin synthases synthesize the sphingolipid
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MOB1, Medulla oblongata-derived protein, Phosphatidylcholine:ceramide cholinephosphotransferase 1, Protein Mob, SGMS1, SMS1, Sphingomyelin synthase 1, TMEM23, Transmembrane protein 23, hmob33, MOB
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSphingomyelin Synthase 1
Short nameSphingomyelin Synthase 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSphingomyelin Synthase 1 (Antibody to)
Alternative techniqueantibodies
Identity 29799
Gene SGMS1
Long gene name sphingomyelin synthase 1
Synonyms gene TMEM23
Synonyms gene name transmembrane protein 23
Synonyms MOB MGC17342 SMS1
Synonyms name phosphatidylcholine:ceramide cholinephosphotransferase 1
Locus 10q11, 23
Discovery year 2004-03-23
GenBank acession AY280959
Entrez gene record 259230
Pubmed identfication 11841947 14976195
RefSeq identity NM_147156
Classification Sterile alpha motif domain containing
Havana BLAST/BLAT OTTHUMG00000018231

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