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Sphingomyelin Synthase 1 Antibody, ALEXA FLUOR 350

Sphingomyelin Synthase 1 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, Sphingomyelin Synthase 1 Antibody
Also known asAnti-Sphingomyelin Synthase 1 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSphingomyelin Synthase 1
SpecificityThis is a highly specific antibody against Sphingomyelin Synthase 1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range50-100/419
Subcellular locationIntracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sphingomyelin Synthase 1
Gene ID Number259230
Swiss ProtQ86VZ5
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, Major form in macrophages, May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide, Required for cell growth in certain cell types such as HeLa cells, Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide, elevated temperature and exogenously supplied sphingolipids, on to the primary hydroxyl of ceramide, osmotic stress, phosphatidylcholine, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate, sphingomyelin, through transfer of the phosphatidyl head group, Sphingomyelin synthases synthesize the sphingolipid
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms MOB MGC17342 SMS1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetSphingomyelin Synthase 1
Short nameSphingomyelin Synthase 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Sphingomyelin Synthase 1 (Antibody to)
Alternative techniqueantibodies
Identity 29799
Gene SGMS1
Long gene name sphingomyelin synthase 1
Synonyms gene TMEM23
Synonyms gene name transmembrane protein 23
Synonyms name phosphatidylcholine:ceramide cholinephosphotransferase 1
Locus 10q11, 23
Discovery year 2004-03-23
GenBank acession AY280959
Entrez gene record 259230
Pubmed identfication 11841947 14976195
RefSeq identity NM_147156
Classification Sterile alpha motif domain containing
Havana BLAST/BLAT OTTHUMG00000018231

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