Filters

Spinophilin/Neurabin 2 Antibody, ALEXA FLUOR 488

Spinophilin/Neurabin 2 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Spinophilin/Neurabin 2 Antibody
Also known asAnti-Spinophilin/Neurabin 2 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSpinophilin/Neurabin 2
SpecificityThis is a highly specific antibody against Spinophilin/Neurabin 2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range360-410/815
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Spinophilin/Neurabin 2
Gene ID Number84687
Swiss ProtQ96SB3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Believed to target protein phosphatase 1/PP1 to dendritic spines, Binds along the sides of the F-actin, Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling, Binds to actin filaments (F-actin) and shows cross-linking activity, May confer to Rac signaling specificity by binding to both, May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton, May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction, Modulates excitatory synaptic transmission and dendritic spine morphology, Plays a role in regulation of G-protein coupled receptor signaling, Probably regulates p70 S6 kinase activity by forming a complex with TIAM1 (By similarity), RacGEFs and Rac effector proteins, Required for hepatocyte growth factor (HGF)-induced cell migration, and regulates its specificity toward ion channels and other substrates, including dopamine D2 receptors and alpha-adrenergic receptors, such as AMPA-type and NMDA-type glutamate receptors, which are rich in F-actin, Seems to act as a scaffold protein in multiple signaling pathways
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms Neurabin-2, Neurabin-II, PPP1R6, PPP1R9, PPP1R9B, Protein phosphatase 1 regulatory subunit 9B, SPINO, Spinophilin, Spn
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Spinophilin/Neurabin 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetSpinophilin/Neurabin 2
Short nameSpinophilin/Neurabin 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Spinophilin/Neurabin 2 (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter