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Spinophilin/Neurabin 2 Antibody, Cy3 Conjugated

Spinophilin/Neurabin 2 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, Spinophilin/Neurabin 2 Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSpinophilin/Neurabin 2
SpecificityThis is a highly specific antibody against Spinophilin/Neurabin 2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range360-410/815
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human Spinophilin/Neurabin 2
Gene ID number84687
Swiss ProtQ96SB3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Believed to target protein phosphatase 1/PP1 to dendritic spines, Binds along the sides of the F-actin, Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling, Binds to actin filaments (F-actin) and shows cross-linking activity, May confer to Rac signaling specificity by binding to both, May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton, May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction, Modulates excitatory synaptic transmission and dendritic spine morphology, Plays a role in regulation of G-protein coupled receptor signaling, Probably regulates p70 S6 kinase activity by forming a complex with TIAM1 (By similarity), RacGEFs and Rac effector proteins, Required for hepatocyte growth factor (HGF)-induced cell migration, and regulates its specificity toward ion channels and other substrates, including dopamine D2 receptors and alpha-adrenergic receptors, such as AMPA-type and NMDA-type glutamate receptors, which are rich in F-actin, Seems to act as a scaffold protein in multiple signaling pathways
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms Neurabin-2, Neurabin-II, PPP1R6, PPP1R9, PPP1R9B, Protein phosphatase 1 regulatory subunit 9B, SPINO, Spinophilin, Spn
Properties 1 of the Spinophilin/Neurabin 2 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSpinophilin/Neurabin 2 Conjugated
Short name Conjugated, Spinophilin/Neurabin 2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, Spinophilin/Neurabin 2 (Antibody to)
Alternative techniqueantibodies

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