Name : SPO11 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3416344291
| Long name | SPO11 Primary Polyclonal Antibody |
| Also known as | SPO11 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SPO11 |
| Specificity | This is a highly specific antibody against SPO11 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPO11 |
| Gene ID number | 23626 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility, Expression of the Spo11 is detected mainly in the testis, The DSBs are located mostly in promoter regions, The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S, and cluster in domains along the chromosome, cerevisiae, in agreement with its predicted function in the initiation of meiotic recombination, where the chromatin is in an open configuration, Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | MGC39953, Meiotic recombination protein SPO11, SPO 11, SPO11 meiotic protein covalently bound to DSB homolog, SPO11 meiotic protein covalently bound to DSB like, SPO11_HUMAN, Meiotic recombination protein SPO 11 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SPO11 |
| Short name | SPO11 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SPO11 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11250 |
| Gene | SPO11 |
| Long gene name | SPO11, initiator of meiotic double stranded breaks |
| Synonyms gene name | SPO11, cerevisiae) SPO11 meiotic protein covalently bound to DSB , cerevisiae) SPO11 meiotic protein covalently bound to DSB homolog (S, cerevisiae)-like SPO11 meiotic protein covalently bound to DSB-like (S, meiotic protein covalently bound to DSB (S |
| Synonyms | CT35 SPATA43 TOPVIA |
| Synonyms name | cancer/testis antigen 35 spermatogenesis associated 43 |
| Locus | 20q13, 31 |
| Discovery year | 1999-12-02 |
| GenBank acession | AF169385 |
| Entrez gene record | 23626 |
| Pubmed identfication | 10534401 26995551 |
| RefSeq identity | NM_012444 |
| Havana BLAST/BLAT | OTTHUMG00000032817 |