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SPO11 Antibody

SPO11 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameSPO11 Primary Polyclonal Antibody
Also known asSPO11 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSPO11
SpecificityThis is a highly specific antibody against SPO11
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPO11
Gene ID number23626
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Disruption of Spo11 leads to severe gonadal abnormalities from defective meiosis and results in infertility, Expression of the Spo11 is detected mainly in the testis, The DSBs are located mostly in promoter regions, The Spo11 protein initiates meiotic recombination by generating DNA double-strand breaks (DSBs) and is required for meiotic synapsis in S, and cluster in domains along the chromosome, cerevisiae, in agreement with its predicted function in the initiation of meiotic recombination, where the chromatin is in an open configuration, Spo11 is a type II topoisomerase that is thought to generate the chromosome breaks that initiate meiotic recombination
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MGC39953, Meiotic recombination protein SPO11, SPO 11, SPO11 meiotic protein covalently bound to DSB homolog, SPO11 meiotic protein covalently bound to DSB like, SPO11_HUMAN, Meiotic recombination protein SPO 11
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSPO11
Short nameSPO11 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSPO11 (Antibody to)
Alternative techniqueantibodies
Identity 11250
Gene SPO11
Long gene name SPO11, initiator of meiotic double stranded breaks
Synonyms gene name SPO11, cerevisiae) SPO11 meiotic protein covalently bound to DSB , cerevisiae) SPO11 meiotic protein covalently bound to DSB homolog (S, cerevisiae)-like SPO11 meiotic protein covalently bound to DSB-like (S, meiotic protein covalently bound to DSB (S
Synonyms CT35 SPATA43 TOPVIA
Synonyms name cancer/testis antigen 35 spermatogenesis associated 43
Locus 20q13, 31
Discovery year 1999-12-02
GenBank acession AF169385
Entrez gene record 23626
Pubmed identfication 10534401 26995551
RefSeq identity NM_012444
Havana BLAST/BLAT OTTHUMG00000032817

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