Name : SPOCK1/Testican 1 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2556219671
| Long name | ALEXA FLUOR 555 Conjugated, SPOCK1/Testican 1 Polyclonal Antibody |
| Also known as | Anti-SPOCK1/Testican 1 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SPOCK1/Testican 1 |
| Specificity | This is a highly specific antibody against SPOCK1/Testican 1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPOCK1/Testican 1 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | After a neural injury, Expression of Testicans is detected in a variety of tissues, Family members include Testican-1, Most Testicans inhibit MT-MMPs, Testican-1 expression is upregulated in astrocyte cells in order to inhibit the ability of the protein Neuro-2a to form neurite extensions, Testican-1 is also a component of joint and of the growth plate cartilage that may participate in the regulation of matrix turnover, Testican-1 is specifically expressed in the thalamus of the brain, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, also designated the BM-40/SPARC/osteonectin family, and is upregulated in activated astroglial cells of the cerebrum where it mediates neuronal attachment and matrix metalloproteinase activation, but is most abundant in brain, calcium-binding, designated N-Tes, extracellular, is composed of highly conserved, such as a cerebral stroke, sulfate proteoglycans, thereby inhibiting the activity of pro-MMP-2, The Testican family |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | testican-1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | SPOCK1/Testican 1 |
| Short name | SPOCK1/Testican 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, acidic, cwcv and kazal-like domains proteoglycan (testican) 1/Testican 1 (Antibody to), cysteine-rich (osteonectin)/osteonectin, secreted protein |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, SPOCK and TESTICAN and TIC1, SPOCK1 and IDBG-46103 and ENSG00000152377 and 6695, SPOCK1 and IDBG-645860 and ENSBTAG00000003502 and 511211, Spock1 and IDBG-157690 and ENSMUSG00000056222 and 20745, cwcv and kazal-like domains proteoglycan (testican) 1, metalloendopeptidase inhibitor activity, this GO :0001558 and regulation of cell growth and biological process this GO :0001764 and neuron migration and biological process this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0004869 and cysteine-type endopeptidase inhibitor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0008191 and metalloendopeptidase inhibitor activity and molecular function this GO :0010812 and negative regulation of cell-substrate adhesion and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0014069 and postsynaptic density and cellular component this GO :0016528 and sarcoplasm and cellular component this GO :0021953 and central nervous system neuron differentiation and biological process this GO :0022008 and neurogenesis and biological process this GO :0031594 and neuromuscular junction and cellular component this GO :0033268 and node of Ranvier and cellular component, this GO :0004867: serine-type endopeptidase inhibitor activity, this GO :0004867: serine-type endopeptidase inhibitor activity and also this GO :0004869: cysteine-type endopeptidase inhibitor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008191: metalloendopeptidase inhibitor activity, this GO :0004869: cysteine-type endopeptidase inhibitor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008191: metalloendopeptidase inhibitor activity, sparc/osteonectin |
| Identity | 11251 |
| Gene | SPOCK1 |
| Long gene name | SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 |
| Synonyms gene | TIC1 SPOCK |
| Synonyms gene name | cwcv and kazal-like domains proteoglycan (testican) , sparc/osteonectin |
| Locus | 5q31, 2 |
| Discovery year | 1995-10-02 |
| GenBank acession | AF231124 |
| Entrez gene record | 6695 |
| Pubmed identfication | 9545645 |
| RefSeq identity | NM_004598 |
| Classification | SPARC family |
| Havana BLAST/BLAT | OTTHUMG00000129157 |