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SPR/Sepiapterin reductase Antibody, Cy7 Conjugated

SPR/Sepiapterin reductase Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, SPR/Sepiapterin reductase Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSPR/Sepiapterin reductase
SpecificityThis is a highly specific antibody against SPR/Sepiapterin reductase
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Sepiapterin reductase
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BH4 is an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, In addition, In addition, Mutations in the gene encoding SPR can cause sepiapterin reductase deficiency, SPR functions as an NADH-dependent aldo-keto reductase and specifically catalyzes the reduction of pteridine derivatives, SPR mRNA expression is increased in the brain of Parkinsonâ, SPR plays an important role in tetrahydrobiopterin (BH4) biosynthesis, Sepiapterin reductase deficiency interferes with BH4 synthesis, a monoamine neurotransmitter deficiency without hyperphenylalaninemia, also known as sepiapterin reductase, catalyzing the final reduction step of the synthesis pathway, is a homodimeric cytoplasmic protein that belongs to the sepiapterin reductase family, resulting in DOPA-responsive dystonia and a variety of other human diseases, suggesting that SPR may play a role in PD, tyrosine and phenylalanine) and is required for proper dopamine synthesis, &euro, &trade, SPR, s Disease (PD) patients
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms SDR38C1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetSPR/Sepiapterin reductase Conjugated
Short name Conjugated, SPR/Sepiapterin reductase Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, SPR/Sepiapterin reductase (Antibody to)
Alternative techniqueantibodies
Identity 11257
Gene SPR
Long gene name sepiapterin reductase (7, 8-dihydrobiopterin:NADP+ oxidoreductase)
Synonyms name member 1 , short chain dehydrogenase/reductase family 38C
Locus 2p13, 2
Discovery year 1991-12-05
Entrez gene record 6697
Pubmed identfication 1883349 19027726
Classification Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000129777
Locus Specific Databases BIOMBD

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