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SPR/Sepiapterin reductase Antibody, FITC Conjugated

SPR/Sepiapterin reductase Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, SPR/Sepiapterin reductase Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSPR/Sepiapterin reductase
SpecificityThis is a highly specific antibody against SPR/Sepiapterin reductase
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Sepiapterin reductase
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BH4 is an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, In addition, In addition, Mutations in the gene encoding SPR can cause sepiapterin reductase deficiency, SPR functions as an NADH-dependent aldo-keto reductase and specifically catalyzes the reduction of pteridine derivatives, SPR mRNA expression is increased in the brain of Parkinsonâ, SPR plays an important role in tetrahydrobiopterin (BH4) biosynthesis, Sepiapterin reductase deficiency interferes with BH4 synthesis, a monoamine neurotransmitter deficiency without hyperphenylalaninemia, also known as sepiapterin reductase, catalyzing the final reduction step of the synthesis pathway, is a homodimeric cytoplasmic protein that belongs to the sepiapterin reductase family, resulting in DOPA-responsive dystonia and a variety of other human diseases, suggesting that SPR may play a role in PD, tyrosine and phenylalanine) and is required for proper dopamine synthesis, &euro, &trade, SPR, s Disease (PD) patients
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms SDR38C1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSPR/Sepiapterin reductase Conjugated
Short name FITC Conjugated, SPR/Sepiapterin reductase Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, SPR/Sepiapterin reductase (Antibody to)
Alternative techniqueantibodies
Identity 11257
Gene SPR
Long gene name sepiapterin reductase (7, 8-dihydrobiopterin:NADP+ oxidoreductase)
Synonyms name member 1 , short chain dehydrogenase/reductase family 38C
Locus 2p13, 2
Discovery year 1991-12-05
Entrez gene record 6697
Pubmed identfication 1883349 19027726
Classification Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000129777
Locus Specific Databases BIOMBD

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