Filters

Sprouty1 Antibody

Sprouty1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSprouty1 Primary Polyclonal Antibody
Also known asSprouty1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSprouty1
SpecificityThis is a highly specific antibody against Sprouty1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Sprouty1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Both Sprouty 1 and 2 are anchored to membranes by palmitoylation, In addition, In conclusion, Mammalian Sprouty homologs share a well-conserved cysteine-rich C-terminal domain with their Drosophila counterparts, Sprouty 2 also functions as a negative regulator of embryonic lung morphogenesis and growth, Sprouty 2 can associate with c-Cbl, The well-conserved C-terminus of Sprouty contains two domains which are necessary for Sprouty 2 co-localization with microtubules and translocation to membrane ruffles, Upon stimulation, a down regulator of RTK signaling, a subset is recruited to the leading edge of the plasma membrane, and inhibits the activities of several growth factors, associate with caveolin-1 in perinuclear and vesicular structures and are phosphorylated on Serine residues, members of Sprouty inhibit FGF and VEGF-mediated cell proliferation, suggesting that they may regulate angiogenesis in normal and disease processes, the C-terminus is required for the inhibition of cell migration and proliferation, Members of the Sprouty family (Sprouty 1-4) are inducible negative regulators of growth factors that act through tyrosine kinase receptors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Protein sprouty homolog 1, SPY1_HUMAN, Sprouty homolog 1, Sprouty homolog 1 antagonist of FGF signaling, Sprouty-1, Spry-1, Spry1, hSPRY1, Sprouty 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSprouty1
Short nameSprouty1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSprouty1 (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter