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SQSTM1 Antibody (p62)

SQSTM1 Antibody (p62) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSQSTM1 (p62)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the SQSTM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis SQSTM1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q13501
PurityAntigen affinity
Description Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene, Mutations in this gene result in sporadic and familial Paget disease of bone, The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals, This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway
ImmunogenA portion of amino acids 383-409 from the human protein was used as the immunogen for this SQSTM1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SQSTM1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSQSTM1 (p62)
Short nameSQSTM1 Antibody (p62)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namesequestosome 1 (Antibody to) (p62)
Alternative techniqueantibodies
Alternative to gene target A170 and OSIL and p60 and p62 and p62B and PDB3 and ZIP3, BT, K63-linked polyubiquitin binding, SQSTM1 and IDBG-61811 and ENSG00000161011 and 8878, Sqstm1 and IDBG-168358 and ENSMUSG00000015837 and 18412, nuclei, this GO :0000407 and pre-autopha this GO somal structure and cellular component this GO :0000932 and cytoplasmic mRNA processing body and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002376 and immune system process and biological process this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005776 and autophagic vacuole and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0006914 and autophagy and biological process this GO :0006950 and response to stress and biological process this GO :0008104 and protein localization and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016197 and endosomal transport and biological process this GO :0016234 and inclusion body and cellular component this GO :0016235 and aggresome and cellular component this GO :0016236 and macroautophagy and biological process this GO :0016239 and positive regulation of macroautophagy and biological process this GO :0016605 and PML body and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030154 and cell differentiation and biological process this GO :0030971 and receptor tyrosine kinase binding and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043122 and regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046578 and regulation of Ras protein signal transduction and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070530 and K63-linked polyubiquitin binding and molecular function this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004674: protein serine/threonine kinase activity, this GO :0004674: protein serine/threonine kinase activity and also this GO :0005080: protein kinase C binding and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019901: protein kinase binding and also this GO :0030971: receptor tyrosine kinase binding and also this GO :0042169: SH2 domain binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0043130: ubiquitin binding and also this GO :0070530: K63-linked polyubiquitin binding, this GO :0005080: protein kinase C binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0019901: protein kinase binding, this GO :0030971: receptor tyrosine kinase binding, this GO :0042169: SH2 domain binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0043130: ubiquitin binding, this GO :0070530: K63-linked polyubiquitin binding, 105440 and IDBG-640935 and ENSBTAG00000015591 and 338045, sequestosome 1
Identity 11280
Gene SQSTM1
Long gene name sequestosome 1
Synonyms gene PDB3 OSIL
Synonyms gene name Paget disease of bone 3 oxidative stress induced like
Synonyms p62 p60 p62B A170
Locus 5q35, 3
Discovery year 2000-06-13
GenBank acession U46751
Entrez gene record 8878
Pubmed identfication 8650207 8551575
Classification Zinc fingers ZZ-type
Havana BLAST/BLAT OTTHUMG00000150643

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