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SRD5A1 Antibody

SRD5A1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSRD5A1 Primary Polyclonal Antibody
Also known asSRD5A1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSRD5A1
SpecificityThis is a highly specific antibody against SRD5A1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SRD5A1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 5a-Reductase 1 is expressed in all portions of the hair follicle, 5a-Reductase 1 is mainly expressed in human breast carcinoma and may play a role in the in situ production and actions of the potent androgen 5a-dihydrotestosterone, 5a-Reductase 1 shows heterogeneity of protein, In addition, In cultured human skin cells, The 5a-Reductase-3a-hydroxysteroid dehydrogenase complex is present in the human brain, The enzyme exists as two isoforms: type 1, and has different levels of transcriptional and translational expression, and type 2, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids, whereas 5a-Reductase 2 is expressed only in mesenchymal portions, which is expressed mainly in the prostate, which is expressed mainly in the skin, which mediates androgen effects on target tissues, Steroid 5a-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5a-dihydro-testosterone
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names S5A1_HUMAN, S5AR 1, SR type 1, Steroid 5-alpha-reductase 1, 3-oxo-5-alpha-steroid 4-dehydrogenase 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSRD5A1
Short nameSRD5A1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSRD5A1 (Antibody to)
Alternative techniqueantibodies
Identity 11284
Gene SRD5A1
Long gene name steroid 5 alpha-reductase 1
Synonyms gene name alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) , steroid-5-alpha-reductase
Synonyms name 3-oxo-5-alpha-steroid 4-dehydrogenase 1
Locus 5p15, 31
Discovery year 1991-05-21
GenBank acession M32313
Entrez gene record 6715
Pubmed identfication 1686016
RefSeq identity NM_001047
Havana BLAST/BLAT OTTHUMG00000090456

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