SRD5A1 Antibody, Biotin Conjugated

SRD5A1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, SRD5A1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	SRD5A1
Specificity	This is a highly specific antibody against SRD5A1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human SRD5A1
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	5a-Reductase 1 is expressed in all portions of the hair follicle, 5a-Reductase 1 is mainly expressed in human breast carcinoma and may play a role in the in situ production and actions of the potent androgen 5a-dihydrotestosterone, 5a-Reductase 1 shows heterogeneity of protein, In addition, In cultured human skin cells, The 5a-Reductase-3a-hydroxysteroid dehydrogenase complex is present in the human brain, The enzyme exists as two isoforms: type 1, and has different levels of transcriptional and translational expression, and type 2, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids, whereas 5a-Reductase 2 is expressed only in mesenchymal portions, which is expressed mainly in the prostate, which is expressed mainly in the skin, which mediates androgen effects on target tissues, Steroid 5a-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5a-dihydro-testosterone
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	SRD5A1 Conjugated
Short name	Conjugated, SRD5A1 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, SRD5A1 (Antibody to)
Alternative technique	antibodies
Identity	11284
Gene	SRD5A1
Long gene name	steroid 5 alpha-reductase 1
Synonyms gene name	alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) , steroid-5-alpha-reductase
Synonyms name	3-oxo-5-alpha-steroid 4-dehydrogenase 1
Locus	5p15, 31
Discovery year	1991-05-21
GenBank acession	M32313
Entrez gene record	6715
Pubmed identfication	1686016
RefSeq identity	NM_001047
Havana BLAST/BLAT	OTTHUMG00000090456

SRD5A1 Antibody, Biotin Conjugated

SRD5A1 Antibody, Biotin Conjugated size: 0.1ml 333

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