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SREBP-1/2 Antibody, ALEXA FLUOR 350

SREBP-1/2 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, SREBP-1/2 Polyclonal Antibody
Also known asAnti-SREBP-1/2 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSREBP-1/2
SpecificityThis is a highly specific antibody against SREBP-1/2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range300-350/1147
Subcellular locationIntracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SREBP-1
Gene ID Number6720, 6721
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Belongs to the SREBP family, Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'), COPII-coated vesicle membrane, Cytoplasmic vesicle, Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein, Golgi apparatus membrane, Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'), Interacts with LMNA, Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters, Multi-pass membrane protein, Multi-pass membrane protein, Multi-pass membrane protein, Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols, Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway, [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane, [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus, [SUBUNIT] Forms a tight complex with SCAP in the ER membrane, Transcriptional activator required for lipid homeostasis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms ADD 1, BHLHD1, D630008H06, SREBF 1, SREBF1, SREBP 1, SREBP 1c, SREBP1, Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1, Sterol regulatory element binding protein 1, Sterol regulatory element binding transcription factor 1, Sterol regulatory element binding protein 1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetSREBP-1/2
Short nameSREBP-1/2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, SREBP-1/2 (Antibody to)
Alternative techniqueantibodies

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