Filters

SREBP-1/2 Antibody, FITC Conjugated

SREBP-1/2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, SREBP-1/2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSREBP-1/2
SpecificityThis is a highly specific antibody against SREBP-1/2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range300-350/1147
Subcellular locationIntracellular
SourceKLH conjugated synthetic peptide derived from human SREBP-1
Gene ID number6720, 6721
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Belongs to the SREBP family, Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'), COPII-coated vesicle membrane, Cytoplasmic vesicle, Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein, Golgi apparatus membrane, Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'), Interacts with LMNA, Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters, Multi-pass membrane protein, Multi-pass membrane protein, Multi-pass membrane protein, Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols, Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway, [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane, [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus, [SUBUNIT] Forms a tight complex with SCAP in the ER membrane, Transcriptional activator required for lipid homeostasis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ADD 1, BHLHD1, D630008H06, SREBF 1, SREBF1, SREBP 1, SREBP 1c, SREBP1, Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1, Sterol regulatory element binding protein 1, Sterol regulatory element binding transcription factor 1, Sterol regulatory element binding protein 1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSREBP-1/2 Conjugated
Short name FITC Conjugated, SREBP-1/2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, SREBP-1/2 (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter