| Long name | SRF Primary Polyclonal Antibody |
| Also known as | SRF PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SRF |
| Specificity | This is a highly specific antibody against SRF |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 115-165/508 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SRF |
| Gene ID number | 6722 |
| Swiss Prot | P11831 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Required for cardiac differentiation and maturation, a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS), SRF is a transcription factor that binds to the serum response element (SRE) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | SRF, Serum response factor, MCM1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SRF |
| Short name | SRF Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | serum response factor (c-fos serum response element-binding transcription factor) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007015 and actin filament organization and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007369 and gastrulation and biological process this GO :0007507 and heart development and biological process this GO :0007616 and long-term memory and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008306 and associative learning and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009725 and response to hormone and biological process this GO :0010669 and epithelial structure maintenance and biological process this GO :0010735 and positive regulation of transcription via serum response element binding and biological process this GO :0010736 and serum response element binding and molecular function this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0021766 and hippocampus development and biological process this GO :0022028 and tangential migration from the subventricular zone to the olfactory bulb and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030038 and contractile actin filament bundle assembly and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030168 and platelet activation and biological process this GO :0030220 and platelet formation and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0031175 and neuron projection development and biological process this GO :0031490 and chromatin DNA binding and molecular function this GO :0033561 and regulation of water loss via skin and biological process this GO :0034097 and response to cytokine and biological process this GO :0035855 and megakaryocyte development and biological process this GO :0035912 and dorsal aorta morphogenesis and biological process this GO :0042789 and mRNA transcription from RNA polymerase II promoter and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043149 and stress fiber assembly and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043589 and skin morphogenesis and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045214 and sarcomere organization and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045987 and positive regulation of smooth muscle contraction and biological process this GO :0046016 and positive regulation of transcription by glucose and biological process this GO :0046716 and muscle cell cellular homeostasis and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048589 and developmental growth and biological process this GO :0048666 and neuron development and biological process this GO :0048821 and erythrocyte development and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051150 and regulation of smooth muscle cell differentiation and biological process this GO :0051491 and positive regulation of filopodium assembly and biological process this GO :0055003 and cardiac myofibril assembly and biological process this GO :0060055 and angiogenesis involved in wound healing and biological process this GO :0060218 and hematopoietic stem cell differentiation and biological process this GO :0060261 and positive regulation of transcription initiation from RNA polymerase II promoter and biological process this GO :0060292 and long term synaptic depression and biological process this GO :0060347 and heart trabecula formation and biological process this GO :0060947 and cardiac vascular smooth muscle cell differentiation and biological process this GO :0061029 and eyelid development in camera-type eye and biological process this GO :0070830 and tight junction assembly and biological process this GO :0071333 and cellular response to glucose stimulus and biological process this GO :0090009 and primitive streak formation and biological process this GO :0090136 and epithelial cell-cell adhesion and biological process this GO :0090398 and cellular senescence and biological process this GO :1900222 and negative regulation of beta-amyloid clearance and biological process, MCM1, SRF and IDBG-87849 and ENSG00000112658 and 6722, Srf and IDBG-187355 and ENSMUSG00000015605 and 20807, nuclei, protein dimerization activity, this GO :0000790 and nuclear chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000983 and RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and molecular function this GO :0001076 and RNA polymerase II transcription factor binding transcription factor activity and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001228 and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001569 and patterning of blood vessels and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001707 and mesoderm formation and biological process this GO :0001764 and neuron migration and biological process this GO :0001829 and trophectodermal cell differentiation and biological process this GO :0001947 and heart looping and biological process this GO :0002011 and morphogenesis of an epithelial sheet and biological process this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0002521 and leukocyte differentiation and biological process this GO :0003257 and positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006355 and regulation of transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and also this GO :0001076: RNA polymerase II transcription factor binding transcription factor activity and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001228: RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0010736: serum response element binding and also this GO :0031490: chromatin DNA binding and also this GO :0042803: protein homodimerization activity and also this GO :0043565: sequence-specific DNA binding and also this GO :0046983: protein dimerization activity, this GO :0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, this GO :0001076: RNA polymerase II transcription factor binding transcription factor activity, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001228: RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0010736: serum response element binding, this GO :0031490: chromatin DNA binding, this GO :0042803: protein homodimerization activity, this GO :0043565: sequence-specific DNA binding, this GO :0046983: protein dimerization activity, 51656 and IDBG-631571 and ENSBTAG00000012777 and 533039, serum response factor (c-fos serum response element-binding transcription factor) |
| Identity | 11291 |
| Gene | SRF |
| Long gene name | serum response factor |
| Synonyms | MCM1 |
| Synonyms name | cerevisiae) c-fos serum response element-binding transcription factor , minichromosome maintenance 1 homolog (S |
| Locus | 6p21, 1 |
| Discovery year | 1995-02-10 |
| GenBank acession | J03161 |
| Entrez gene record | 6722 |
| Pubmed identfication | 3203386 7744019 |
| RefSeq identity | NM_003131 |
| Classification | MADS box family |
| Havana BLAST/BLAT | OTTHUMG00000014722 |
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