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SRGN Antibody

SRGN Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSRGN Primary Polyclonal Antibody
Also known asSRGN PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSRGN
SpecificityThis is a highly specific antibody against SRGN
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Serglycin/SRGN Polyclonal Antibody
Gene ID number5552
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Inhibits bone mineralization, Mediates processing of MMP2, Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis, Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils, Regulates the secretion of TNF-alpha and may also regulate protease secretion, Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes, Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cytolytic granule proteoglycan core protein, Hematopoetic proteoglycan core protein, Mastocytoma proteoglycan core protein, P, PG19 core protein, PLATELET PROTEOGLYCAN PROTEIN CORE, PPG, PRG, PRG1, PROTEOGLYCAN 1, PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE, Pgsg, Platelet proteoglycan core protein, Proteoglycan 10K core protein, Proteoglycan peptide core protein, SRGN_HUMAN, Secretory granule proteoglycan core protein, Serglycin, Sgc, Srgn, platelet proteoglycan protein core, proteoglycan 1, secretory granule, secretory granule proteoglycan 1, serglycin proteoglycan, Chondroitin sulfate proteoglycan core protein, PG
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSRGN
Short nameSRGN Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameserglycin (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, Extracellular, PPG and PRG and PRG1, SRGN and IDBG-76481 and ENSG00000122862 and 5552, Srgn and IDBG-157635 and ENSMUSG00000020077 and 19073, collagen binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0002576 and platelet degranulation and biological process this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0007596 and blood coagulation and biological process this GO :0008626 and granzyme-mediated apoptotic signaling pathway and biological process this GO :0016485 and protein processing and biological process this GO :0030168 and platelet activation and biological process this GO :0030502 and negative regulation of bone mineralization and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0031214 and biomineral tissue development and biological process this GO :0033364 and mast cell secretory granule organization and biological process this GO :0033371 and T cell secretory granule organization and biological process this GO :0033373 and maintenance of protease location in mast cell secretory granule and biological process this GO :0033382 and maintenance of granzyme B location in T cell secretory granule and biological process this GO :0042588 and zymogen granule and cellular component this GO :0042629 and mast cell granule and cellular component this GO :0050710 and negative regulation of cytokine secretion and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005518: collagen binding, this GO :0005518: collagen binding, 97928 and IDBG-629459 and ENSBTAG00000017863 and 509501, serglycin
Identity 9361
Gene SRGN
Long gene name serglycin
Synonyms gene PRG PRG1
Synonyms gene name proteoglycan 1, secretory granule
Synonyms PPG
Synonyms name serglycin proteoglycan
Locus 10q22, 1
Discovery year 1988-07-22
GenBank acession BC015516
Entrez gene record 5552
RefSeq identity NM_002727
Classification Proteoglycans
Havana BLAST/BLAT OTTHUMG00000018369

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