| Long name | ALEXA FLUOR 594 Conjugated, STAT1 (Tyr701) Polyclonal Antibody |
| Also known as | Anti-STAT1 Tyr701 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | STAT1 Tyr701 |
| Specificity | This is a highly specific antibody against STAT1 Tyr701 |
| Modification | Phosphorylation |
| Modification Site | Tyr701 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human STAT1 around the phosphorylation site of tyrosine 701 |
| Gene ID Number | 6772 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | EGF, In response to cytokines and growth factors, PDGF and IL6, STAT family members are phosphorylated by the receptor associated kinases, This protein can be activated by various ligands including interferon-alpha, This protein mediates the expression of a variety of genes, Two alternatively spliced transcript variants encoding distinct isoforms have been described, [provided by RefSeq], and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators, interferon-gamma, which is thought to be important for cell viability in response to different cell stimuli and pathogens, The protein encoded by this gene is a member of the STAT protein family |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | STAT91 ISGF-3 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | STAT1 (Tyr701) |
| Short name | STAT1 (Tyr701) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | 91kDa (Tyr701) (Antibody to), ALEXA FLUOR 594, signal transducer and activator on transcription 1 |
| Alternative technique | antibodies |
| Alternative to gene target | 91kDa, CANDF7 and IMD31A and IMD31B and IMD31C and ISGF-3 and STAT91, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0007584 and response to nutrient and biological process this GO :0008015 and blood circulation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009617 and response to bacterium and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016032 and viral process and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019899 and enzyme binding and molecular function this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0031730 and CCR5 chemokine receptor binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0034097 and response to cytokine and biological process this GO :0034240 and negative regulation of macrophage fusion and biological process this GO :0035458 and cellular response to interferon-beta and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0051591 and response to cAMP and biological process this GO :0051607 and defense response to virus and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0061326 and renal tubule development and biological process this GO :0072136 and metanephric mesenchymal cell proliferation involved in metanephros development and biological process this GO :0072162 and metanephric mesenchymal cell differentiation and biological process this GO :0072308 and negative regulation of metanephric nephron tubule epithelial cell differentiation and biological process, STAT1 and IDBG-642654 and ENSBTAG00000007867 and 510814, STAT1 and IDBG-77617 and ENSG00000115415 and 6772, Stat1 and IDBG-153162 and ENSMUSG00000026104 and 20846, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0000983 and RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and molecular function this GO :0001937 and negative regulation of endothelial cell proliferation and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003340 and negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and also this GO :0003677: DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0004871: signal transducer activity and also this GO :0005164: tumor necrosis factor receptor binding and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0019899: enzyme binding and also this GO :0031730: CCR5 chemokine receptor binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0043565: sequence-specific DNA binding, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, this GO :0003677: DNA binding, this GO :0003690: double-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0004871: signal transducer activity, this GO :0005164: tumor necrosis factor receptor binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0019899: enzyme binding, this GO :0031730: CCR5 chemokine receptor binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0043565: sequence-specific DNA binding, 515988, signal transducer and activator of transcription 1 |
| Identity | 11362 |
| Gene | STAT1 |
| Long gene name | signal transducer and activator of transcription 1 |
| Synonyms gene name | 91kD signal transducer and activator of transcription 1, 91kDa , signal transducer and activator of transcription 1 |
| Synonyms name | transcription factor ISGF-3 components p91/p84 |
| Locus | 2q32, 2 |
| Discovery year | 1995-11-08 |
| Entrez gene record | 6772 |
| Pubmed identfication | 7885841 |
| RefSeq identity | NM_007315 |
| Classification | SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000132699 |
| Locus Specific Databases | STAT1base: Mutation registry for STAT1 deficiency LRG_111 |
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