Name : STAT4 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9787983411
| Long name | FITC Conjugated, STAT4 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | STAT4 |
| Specificity | This is a highly specific antibody against STAT4 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human STAT4 |
| Gene ID number | 6775 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Alternate splicing results in multiple transcript variants that encode the same protein, Aug 2011], In response to cytokines and growth factors, Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis, STAT family members are phosphorylated by the receptor associated kinases, This protein is essential for mediating responses to IL12 in lymphocytes, [provided by RefSeq, and regulating the differentiation of T helper cells, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators, The protein encoded by this gene is a member of the STAT family of transcription factors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | STAT4 Conjugated |
| Short name | FITC Conjugated, STAT4 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, signal transducer and activator on transcription 4 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0008283 and cell proliferation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0071310 and cellular response to organic substance and biological process, SLEB11, STAT4 and IDBG-642767 and ENSBTAG00000046699 and, STAT4 and IDBG-77625 and ENSG00000138378 and 6775, Stat4 and IDBG-152917 and ENSMUSG00000062939 and 20849, nuclei, sequence-specific DNA binding, this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0004871: signal transducer activity and also this GO :0005509: calcium ion binding and also this GO :0043565: sequence-specific DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0004871: signal transducer activity, this GO :0005509: calcium ion binding, this GO :0043565: sequence-specific DNA binding, signal transducer and activator of transcription 4 |
| Identity | 11365 |
| Gene | STAT4 |
| Long gene name | signal transducer and activator of transcription 4 |
| Locus | 2q32, 2-q32, 3 |
| Discovery year | 1995-11-08 |
| Entrez gene record | 6775 |
| Pubmed identfication | 8007943 8700208 |
| RefSeq identity | NM_003151 |
| Classification | SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000132700 |