Name : STAT6(Thr645) Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN1502297023
| Long name | ALEXA FLUOR 488 Conjugated, STAT6(Thr645) Polyclonal Antibody |
| Also known as | Anti-STAT6 Thr645 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | STAT6 Thr645 |
| Specificity | This is a highly specific antibody against STAT6 Thr645 |
| Modification | Phosphorylation |
| Modification Site | Thr645 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 625-670/841 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from rat STAT6 around the phosphorylation site of tyrosine Thr645 |
| Gene ID Number | 362896 |
| Swiss Prot | Q1KQ07 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Rat, Mouse |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling, Carries out a dual function: signal transduction and activation of transcription |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | D12S1644 IL-4-STAT |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the STAT6(Thr645) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | STAT6(Thr645) |
| Short name | STAT6(Thr645) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, interleukin-4 induced(Thr645) (Antibody to), signal transducer and activator on transcription 6 |
| Alternative technique | antibodies |
| Alternative to gene target | D12S1644 and IL-4-STAT and STAT6B and STAT6C, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007165 and signal transduction and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0033598 and mammary gland epithelial cell proliferation and biological process this GO :0034097 and response to cytokine and biological process this GO :0035771 and interleukin-4-mediated signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048295 and positive regulation of isotype switching to IgE isotypes and biological process this GO :0060443 and mammary gland morphogenesis and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :1902170 and cellular response to reactive nitrogen species and biological process, STAT6 and IDBG-42122 and ENSG00000166888 and 6778, STAT6 and IDBG-635695 and ENSBTAG00000006335 and 353105, Stat6 and IDBG-195602 and ENSMUSG00000002147 and 20852, interleukin-4 induced, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0002296 and T-helper 1 cell lineage commitment and biological process this GO :0002829 and negative regulation of type 2 immune response and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979: RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0004871: signal transducer activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0019903: protein phosphatase binding and also this GO :0042802: identical protein binding and also this GO :0043565: sequence-specific DNA binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0004871: signal transducer activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0019903: protein phosphatase binding, this GO :0042802: identical protein binding, this GO :0043565: sequence-specific DNA binding, signal transducer and activator of transcription 6 |
| Identity | 11368 |
| Gene | STAT6 |
| Long gene name | signal transducer and activator of transcription 6 |
| Synonyms gene name | interleukin-4 induced , signal transducer and activator of transcription 6 |
| Locus | 12q13 |
| Discovery year | 1995-11-09 |
| GenBank acession | BC005823 BQ028928 |
| Entrez gene record | 6778 |
| Pubmed identfication | 9605853 8085155 |
| RefSeq identity | NM_003153 |
| Classification | SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000171194 |