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Stella/DPPA3 Antibody

Stella/DPPA3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameStella/DPPA3 Primary Polyclonal Antibody
Also known asStella/DPPA3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenStella/DPPA3
SpecificityThis is a highly specific antibody against Stella/DPPA3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range100-150/159
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Stella/DPPA3
Gene ID number359787
Swiss ProtQ6W0C5
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also involved in chromatin condensation in oocytogenesis (By similarity), Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, Does not bind paternal chromatin, In zygotes, May be important for the totipotent/pluripotent states continuing through preimplantation development, Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation, which is mainly packed into protamine and does not contain much H3K9me2 mark, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process, Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DPPA3, Developmental pluripotency-associated protein 3, STELLAR, Stella-related protein, STELLA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetStella/DPPA3
Short nameStella/DPPA3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameStella/DPPA3 (Antibody to)
Alternative techniqueantibodies
Identity 19199
Gene DPPA3
Long gene name developmental pluripotency associated 3
Synonyms Stella
Locus 12p13, 31
Discovery year 2003-07-09
GenBank acession AY317075
Entrez gene record 359787
RefSeq identity NM_199286
Havana BLAST/BLAT OTTHUMG00000168434

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