| Alternative name1 | CXCL12, Chemokine (C-X-C Motif) Ligand 12, PBSF, Pre-B cell Growth-stimulating Factor, SCYB12, SDF-1a, SDF1a, TLSF-a, TPAR1) (Biotin), hIRH, Anti-Stromal Cell Derived Factor 1alpha (SDF1 alpha |
| Alternative name2 | CXCL12, Chemokine (C-X-C Motif) Ligand 12, PBSF, Pre-B cell Growth-stimulating Factor, SCYB12, SDF-1a, SDF1a, TLSF-a, TPAR1) (Biotin), hIRH, Stromal Cell Derived Factor 1alpha (SDF1 alpha |
| Alternative name3 | CXCL12, Chemokine (C-X-C Motif) Ligand 12, PBSF, Pre-B cell Growth-stimulating Factor, SCYB12, SDF-1a, SDF1a, TLSF-a, TPAR1) (Biotin), hIRH, Stromal Cell Derived Factor 1alpha (SDF1 alpha |
| Alternative name4 | Stromal Cell Derived Factor 1alpha |
| Alternative name5 | CXCL12, Chemokine (C-X-C Motif) Ligand 12, PBSF, Pre-B cell Growth-stimulating Factor, SCYB12, SDF-1a, SDF1a, TLSF-a, TPAR1) (Biotin), hIRH, Anti -Stromal Cell Derived Factor 1alpha (SDF1 alpha |
| Other names | CXCL12 protein, N/A, OTTHUMP00000019491, OTTHUMP00000019492, OTTHUMP00000216979, OTTHUMP00000216980, chemokine (C-X-C motif) ligand 12, intercrine reduced in hepatomas, pre-B cell growth-stimulating factor, stromal cell-derived factor 1, stromal cell-derived factor 1 isoform alpha |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | CXCL12, IRH, N/A, PBSF, SCYB12, SDF1, SDF1A, SDF1B, TLSF, TPAR1, CXCL12 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | Recognizes SDF-1-alpha |
| Purification method | 98% Purified by affinity chromatography, Affinity > |
| Form/Appearance | 0, Labeled with biotin, Reconstitution: Reconstitute with sterile PBS, This solution can then be diluted into other aqueous solutions, pH 7, to a concentration of 0, 05mg/ml, 1% BSA, 4, Supplied as a lyophilized powder in PBS |
| Concentration | N/A |
| Storage and shipping | For maximum recovery of product, Further dilutions can be made in assay buffer, Reconstitute to nominal volume by adding sterile 40-50% glycerol and For optimal long term storage, Reconstituted product is stable for 12 months productone should be stored at -20 degrees Celsius, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Lyophilized powder Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB), ELISA (EL/EIA) |
| Description | Chemokines, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling, Receptor agonists are often tested for drug development, cell lines and tissues in culture till half confluency, chemokine receptors, ligands , motif chemokines and cytokines are supplied by MBS Polyclonals_1 in 1, For cells |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Conjugation | Biotinylated |
| Gene target | CXCL12, Chemokine (C-X-C Motif) Ligand 12, PBSF, Pre-B Growth-stimulating Factor, SCYB12, SDF-1a, SDF1a, TLSF-a, TPAR1), hIRH, Stromal Derived Factor 1alpha (SDF1 alpha |
| Short name | CXCL12, Chemokine (C-X-C Motif) Ligand 12, PBSF, Pre-B Growth-stimulating Factor, SCYB12, SDF-1a, SDF1a, TLSF-a, TPAR1) ( ) Antibody, hIRH, Stromal Cell Derived Factor 1alpha (SDF1 alpha |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | Biotin |
| Alternative name | Chemokine (C-X-C Motif) Ligand 12, PBSF, Pre-B cellular Growth-stimulating Factor, SCYB12, SDF-1a, SDF1a, TLSF-a, TPAR1) (biotinilated) (Antibody to), chemokine (C-X-C motif) ligand 12, hIRH, Stromal cellular Derived Factor 1alpha (SDF1 a |
| Alternative technique | antibodies |
| Alternative to gene target | CXCL12 and IDBG-632037 and ENSBTAG00000005077 and 613811, CXCL12 and IDBG-71595 and ENSG00000107562 and 6387, CXCR chemokine receptor binding, Cxcl12 and IDBG-180998 and ENSMUSG00000061353 and 20315, Extracellular, IRH and PBSF and SCYB12 and SDF1 and TLSF and TPAR1, this GO :0001569 and patterning of blood vessels and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001667 and ameboidal cell migration and biological process this GO :0001764 and neuron migration and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0005102 and receptor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007281 and germ cell development and biological process this GO :0007420 and brain development and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008015 and blood circulation and biological process this GO :0008045 and motor neuron axon guidance and biological process this GO :0008064 and regulation of actin polymerization or depolymerization and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008344 and adult locomotory behavior and biological process this GO :0008354 and germ cell migration and biological process this GO :0009314 and response to radiation and biological process this GO :0009408 and response to heat and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0022029 and telencephalon cell migration and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031100 and organ regeneration and biological process this GO :0033603 and positive regulation of dopamine secretion and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042379 and chemokine receptor binding and molecular function this GO :0043434 and response to peptide hormone and biological process this GO :0045087 and innate immune response and biological process this GO :0045236 and CXCR chemokine receptor binding and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0048842 and positive regulation of axon extension involved in axon guidance and biological process this GO :0050930 and induction of positive chemotaxis and biological process this GO :0051924 and regulation of calcium ion transport and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0090026 and positive regulation of monocyte chemotaxis and biological process this GO :0090280 and positive regulation of calcium ion import and biological process this GO :1902230 and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :2000107 and negative regulation of leukocyte apoptotic process and biological process this GO :2000406 and positive regulation of T cell migration and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0008009: chemokine activity and also this GO :0008083: growth factor activity and also this GO :0042379: chemokine receptor binding and also this GO :0045236: CXCR chemokine receptor binding, this GO :0008009: chemokine activity, this GO :0008083: growth factor activity, this GO :0042379: chemokine receptor binding, this GO :0045236: CXCR chemokine receptor binding, chemokine (C-X-C motif) ligand 12 |
| Identity | 10672 |
| Gene | CXCL12 |
| Long gene name | C-X-C motif chemokine ligand 12 |
| Synonyms gene | SDF1A SDF1B SDF1 |
| Synonyms gene name | stromal cell-derived factor 1 chemokine (C-X-C motif) ligand 12 |
| Synonyms | SCYB12 SDF-1a SDF-1b PBSF TLSF-a TLSF-b TPAR1 |
| Locus | 10q11, 21 |
| Discovery year | 1994-11-30 |
| GenBank acession | L36033 |
| Entrez gene record | 6387 |
| Pubmed identfication | 7490086 |
| RefSeq identity | NM_000609 |
| Classification | Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT | OTTHUMG00000018054 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue