Filters

STUB1 Antibody

STUB1 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenSTUB1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the STUB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis STUB1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9UNE7
PurityAntigen affinity
Description CHIP E3 controls both the association of Hsp70/Hsp90 chaperones with ErbB2 and the down-regulation of ErbB2 induced by inhibitors of Hsp90, CHIP can interact with the Smad1/Smad4 proteins and block BMP signal transduction through the ubiquitin-mediated degradation of Smad proteins, CHIP functions as a negative regulator of AR transcriptional activity by promoting AR degradation, CHIP is associated with Parkin and enhances its ubiquitin ligase activity related to Parkinson's disease, CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival, Co-chaperone CHIP, modulates the ubiquitylation of mutant Cu/Zn-superoxide dismutase and renders them more susceptible for proteasomal degradation, possibly with another E3 ligase(s), CHIP is an E3 ligase for nNOS whose action is facilitated by (and possibly requires) its interaction with nNOS-bound hsp70
ImmunogenA portion of amino acids 203-231 from the human protein was used as the immunogen for this STUB1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the STUB1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetSTUB1
Short nameSTUB1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSTUB1 (Antibody to)
Alternative techniqueantibodies
Identity 11427
Gene STUB1
Long gene name STIP1 homology and U-box containing protein 1
Synonyms gene name E3 ubiquitin protein ligase , STIP1 homology and U-box containing protein 1 STIP1 homology and U-box containing protein 1
Synonyms UBOX1 CHIP SDCCAG7 HSPABP2 NY-CO-7
Locus 16p13, 3
Discovery year 1999-11-25
GenBank acession AF039689
Entrez gene record 10273
Pubmed identfication 10330192 9610721
RefSeq identity NM_005861
Classification Tetratricopeptide repeat domain containing U-box domain containing
Havana BLAST/BLAT OTTHUMG00000121140

Similar products

Subscribe to our Newsletter