Name : SUMO 1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6478824944
| Long name | SUMO 1 Primary Polyclonal Antibody |
| Also known as | SUMO 1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SUMO 1 |
| Specificity | There is a chance that this antibody will cross-react with SUMO13, This is a highly specific antibody against SUMO 1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 20-70/101 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SUMO 1 |
| Gene ID number | 7341 |
| Swiss Prot | P63165 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, DNA replication and repair, Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2, May also regulate a network of genes involved in palate development, Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins, RANBP2 or CBX4, This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, and can be promoted by E3 ligases such as PIAS1-4, mitosis and signal transduction, Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GAP-modifying protein 1, GMP1, OK/SW-cl, SMT3 homolog 3, SMT3C, SMT3H3, SUMO-1, SUMO1, Sentrin, Smt3C, UBL1, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1, 43, Small ubiquitin-related modifier 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SUMO 1 |
| Short name | SUMO 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SUMO 1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 30660 |
| Gene | SAE1 |
| Long gene name | SUMO1 activating enzyme subunit 1 |
| Synonyms | AOS1 FLJ3091 Sua1 |
| Synonyms name | activator Of sumo 1 |
| Locus | 19q13, 32 |
| Discovery year | 2006-10-31 |
| GenBank acession | BC018271 |
| Entrez gene record | 10055 |
| Pubmed identfication | 10187858 9920803 10217437 |
| RefSeq identity | NM_005500 |
| Classification | Ubiquitin like modifier activating enzymes |
| Havana BLAST/BLAT | OTTHUMG00000183464 |