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SUMO 1 Antibody, Biotin Conjugated

SUMO 1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, SUMO 1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSUMO 1
Specificity There is a chance that this antibody will cross-react with SUMO13, This is a highly specific antibody against SUMO 1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range20-70/101
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human SUMO 1
Gene ID number7341
Swiss ProtP63165
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, DNA replication and repair, Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2, May also regulate a network of genes involved in palate development, Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins, RANBP2 or CBX4, This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, and can be promoted by E3 ligases such as PIAS1-4, mitosis and signal transduction, Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms GAP-modifying protein 1, GMP1, OK/SW-cl, SMT3 homolog 3, SMT3C, SMT3H3, SUMO-1, SUMO1, Sentrin, Smt3C, UBL1, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1, 43, Small ubiquitin-related modifier 1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSUMO 1 Conjugated
Short name Conjugated, SUMO 1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, SUMO 1 (Antibody to)
Alternative techniqueantibodies

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