Name : SUMO1 (66AT1273.94) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN4381258028
| Long name | 94) Monoclonal Antibody, SUMO1 (66AT1273 |
| Also known as | 94) Monoclonal Antibody, SUMO1 (66AT1273 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SUMO1 |
| Specificity | This is a highly specific antibody against SUMO1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 66AT1273, 94 |
| Source | Purified recombinant GST-SUMO1 fusion protein was used as immunogen |
| Gene ID number | 7341 |
| Swiss Prot | P63165 |
| Tested Applications | FCM, IHC-P, WB |
| Recommended dilutions | FCM(1:25), IHC-P(1:25) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, Covalently attached to ZFHX3 (PubMed:24651376), Covalently attached to the voltage-gated potassium channel KCNB1, DNA replication and repair, Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2, May also regulate a network of genes involved in palate development, Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins, RANBP2 or CBX4, This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, and can be promoted by E3 ligases such as PIAS1-4, mitosis and signal transduction, this modulates the gating characteristics of KCNB1 (PubMed:19223394), Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer |
| Purification method | This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GAP-modifying protein 1, GMP1, OFC10, OK/SW-cl, PIC1, SENP2, SMT3, SMT3 homolog 3, SMT3C, SMT3H3, SUMO-1, SUMO1, Sentrin, Small ubiquitin-related modifier 1, UBL1, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1, 43, DAP1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 94) Monoclonal, SUMO1 (66AT1273 |
| Short name | 94) Monoclonal Antibody, SUMO1 (66AT1273 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 94) monoclonal (Antibody to), SUMO1 (66AT1273 |
| Alternative technique | antibodies |
| Identity | 12502 |
| Gene | SUMO1 |
| Long gene name | small ubiquitin-like modifier 1 |
| Synonyms gene | UBL1 |
| Synonyms gene name | cerevisiae) , ubiquitin-like 1 (sentrin) SMT3 suppressor of mif two 3 homolog 1 (yeast) SMT3 suppressor of mif two 3 homolog 1 (S |
| Synonyms | PIC1 GMP1 SMT3C SUMO-1 SMT3H3 OFC10 |
| Locus | 2q33, 1 |
| Discovery year | 1996-06-04 |
| GenBank acession | U38784 |
| Entrez gene record | 7341 |
| Pubmed identfication | 8812453 8906799 |
| RefSeq identity | NM_003352 |
| Havana BLAST/BLAT | OTTHUMG00000132839 |