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SUMO1 (66AT1273.94) Monoclonal Antibody

SUMO1 (66AT1273.94) Monoclonal Antibody size: 0.1ml 211

Price 211
Size 0.1ml
Long name94) Monoclonal Antibody, SUMO1 (66AT1273
Also known as94) Monoclonal Antibody, SUMO1 (66AT1273
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSUMO1
SpecificityThis is a highly specific antibody against SUMO1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number66AT1273, 94
SourcePurified recombinant GST-SUMO1 fusion protein was used as immunogen
Gene ID number7341
Swiss ProtP63165
Tested Applications FCM, IHC-P, WB
Recommended dilutions FCM(1:25), IHC-P(1:25)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, Covalently attached to ZFHX3 (PubMed:24651376), Covalently attached to the voltage-gated potassium channel KCNB1, DNA replication and repair, Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2, May also regulate a network of genes involved in palate development, Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins, RANBP2 or CBX4, This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, and can be promoted by E3 ligases such as PIAS1-4, mitosis and signal transduction, this modulates the gating characteristics of KCNB1 (PubMed:19223394), Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer
Purification method This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GAP-modifying protein 1, GMP1, OFC10, OK/SW-cl, PIC1, SENP2, SMT3, SMT3 homolog 3, SMT3C, SMT3H3, SUMO-1, SUMO1, Sentrin, Small ubiquitin-related modifier 1, UBL1, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1, 43, DAP1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target94) Monoclonal, SUMO1 (66AT1273
Short name94) Monoclonal Antibody, SUMO1 (66AT1273
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name94) monoclonal (Antibody to), SUMO1 (66AT1273
Alternative techniqueantibodies
Identity 12502
Gene SUMO1
Long gene name small ubiquitin-like modifier 1
Synonyms gene UBL1
Synonyms gene name cerevisiae) , ubiquitin-like 1 (sentrin) SMT3 suppressor of mif two 3 homolog 1 (yeast) SMT3 suppressor of mif two 3 homolog 1 (S
Synonyms PIC1 GMP1 SMT3C SUMO-1 SMT3H3 OFC10
Locus 2q33, 1
Discovery year 1996-06-04
GenBank acession U38784
Entrez gene record 7341
Pubmed identfication 8812453 8906799
RefSeq identity NM_003352
Havana BLAST/BLAT OTTHUMG00000132839

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