Name : SUMO2 (973CT8.1.1) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN7309858726
| Long name | 1, 1) Monoclonal Antibody, SUMO2 (973CT8 |
| Also known as | 1, 1) Monoclonal Antibody, SUMO2 (973CT8 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SUMO2 |
| Specificity | This is a highly specific antibody against SUMO2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1, 1, 973CT8 |
| Source | Purified His-tagged SUMO2 protein was used to produced this monoclonal antibody |
| Gene ID number | 6613 |
| Swiss Prot | P61956 |
| Tested Applications | IF, WB |
| Recommended dilutions | WB(1:1000), IF(1:25) |
| Cross reactivity | Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | CBX4 or ZNF451 (PubMed:26524494), Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, DNA replication and repair, Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744), Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (PubMed:18408734, PubMed:18538659, PubMed:21965678, PubMed:9556629), RANBP2, This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, and can be promoted by an E3 ligase such as PIAS1-4, mitosis and signal transduction, Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer |
| Purification method | This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | SMT3 homolog 2, SMT3B, SMT3H2, SUMO-2, SUMO-3, SUMO2, SUMO3, Sentrin-2, Small ubiquitin-related modifier 2, Smt3A, Ubiquitin-like protein SMT3B, HSMT3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 1, 1) Monoclonal, SUMO2 (973CT8 |
| Short name | 1, 1) Monoclonal Antibody, SUMO2 (973CT8 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 1, 1) monoclonal (Antibody to), SUMO2 (973CT8 |
| Alternative technique | antibodies |
| Identity | 11125 |
| Gene | SUMO2 |
| Long gene name | small ubiquitin-like modifier 2 |
| Synonyms gene | SMT3H2 |
| Synonyms gene name | SMT3 (suppressor of mif two 3, cerevisiae) , yeast) homolog 2 SMT3 suppressor of mif two 3 homolog 2 (yeast) SMT3 suppressor of mif two 3 homolog 2 (S |
| Synonyms | SMT3B |
| Locus | 17q25 |
| Discovery year | 1997-01-29 |
| Entrez gene record | 6613 |
| Pubmed identfication | 8630065 |
| RefSeq identity | NM_006937 |
| Havana BLAST/BLAT | OTTHUMG00000179481 |