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Supervillin Antibody

Supervillin Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSupervillin Primary Polyclonal Antibody
Also known asSupervillin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSupervillin
SpecificityThis is a highly specific antibody against Supervillin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range80-130/2214
Subcellular locationCell membrane
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Supervillin
Gene ID number6840
Swiss ProtO95425
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Appears to be involved in myosin II assembly, Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation, Isoform 2 may be involved in modulation of focal adhesions, May modulate myosin II regulation through MLCK during cell spreading, May play a role in invadopodial function, Plays a role in cytokinesis through KIF14 interaction (By similarity), Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6, an initial step in cell migration, Forms a high-affinity link between the actin cytoskeleton and the membrane
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Archvillin, SVIL, p205/p250, Supervillin
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSupervillin
Short nameSupervillin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSupervillin (Antibody to)
Alternative techniqueantibodies
Identity 11480
Gene SVIL
Long gene name supervillin
Synonyms name archvillin
Locus 10p11, 23
Discovery year 1998-05-07
GenBank acession AF051851
Entrez gene record 6840
Pubmed identfication 9382871
Classification Gelsolin/villins
Havana BLAST/BLAT OTTHUMG00000017882

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