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Supervillin Antibody, ALEXA FLUOR 488

Supervillin Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Supervillin Polyclonal Antibody
Also known asAnti-Supervillin PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSupervillin
SpecificityThis is a highly specific antibody against Supervillin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range80-130/2214
Subcellular locationCell membrane
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Supervillin
Gene ID Number6840
Swiss ProtO95425
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Appears to be involved in myosin II assembly, Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation, Isoform 2 may be involved in modulation of focal adhesions, May modulate myosin II regulation through MLCK during cell spreading, May play a role in invadopodial function, Plays a role in cytokinesis through KIF14 interaction (By similarity), Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6, an initial step in cell migration, Forms a high-affinity link between the actin cytoskeleton and the membrane
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Supervillin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetSupervillin
Short nameSupervillin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Supervillin (Antibody to)
Alternative techniqueantibodies
Identity 11480
Gene SVIL
Long gene name supervillin
Synonyms name archvillin
Locus 10p11, 23
Discovery year 1998-05-07
GenBank acession AF051851
Entrez gene record 6840
Pubmed identfication 9382871
Classification Gelsolin/villins
Havana BLAST/BLAT OTTHUMG00000017882

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