Name : Supervillin Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6432016056
| Long name | ALEXA FLUOR 647 Conjugated, Supervillin Polyclonal Antibody |
| Also known as | Anti-Supervillin PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Supervillin |
| Specificity | This is a highly specific antibody against Supervillin |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 80-130/2214 |
| Subcellular location | Cell membrane |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Supervillin |
| Gene ID Number | 6840 |
| Swiss Prot | O95425 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Appears to be involved in myosin II assembly, Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation, Isoform 2 may be involved in modulation of focal adhesions, May modulate myosin II regulation through MLCK during cell spreading, May play a role in invadopodial function, Plays a role in cytokinesis through KIF14 interaction (By similarity), Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6, an initial step in cell migration, Forms a high-affinity link between the actin cytoskeleton and the membrane |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Supervillin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | Supervillin |
| Short name | Supervillin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, Supervillin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11480 |
| Gene | SVIL |
| Long gene name | supervillin |
| Synonyms name | archvillin |
| Locus | 10p11, 23 |
| Discovery year | 1998-05-07 |
| GenBank acession | AF051851 |
| Entrez gene record | 6840 |
| Pubmed identfication | 9382871 |
| Classification | Gelsolin/villins |
| Havana BLAST/BLAT | OTTHUMG00000017882 |