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Survivin Antibody, ALEXA FLUOR 555

Survivin Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, Survivin Polyclonal Antibody
Also known asAnti-Survivin PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSurvivin
SpecificityThis is a highly specific antibody against Survivin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range93-142/142
Subcellular locationHelical
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Survivin
Gene ID Number332
Swiss ProtO15392
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as an important regulator of the localization of this complex, Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis, Inhibitor of CASP3 and CASP7, Isoform 2 and isoform 3 do not appear to play vital roles in mitosis, Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform, May counteract a default induction of apoptosis in G2/M phase, May play a role in neoplasia, The acetylated form represses STAT3 transactivation of target gene promoters, The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules, directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules, Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms EPR-1 survivin
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetSurvivin
Short nameSurvivin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, Survivin (Antibody to)
Alternative techniqueantibodies
Identity 593
Gene BIRC5
Long gene name baculoviral IAP repeat containing 5
Synonyms gene API4
Synonyms gene name apoptosis inhibitor 4 baculoviral IAP repeat-containing 5
Synonyms name survivin variant 3 alpha
Locus 17q25, 3
Discovery year 1998-06-10
GenBank acession U75285
Entrez gene record 332
Pubmed identfication 8106347 7947793
RefSeq identity NM_001168
Classification Baculoviral IAP repeat containing Chromosomal passenger complex
Havana BLAST/BLAT OTTHUMG00000177505

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