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SUV39H1 Antibody

SUV39H1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSUV39H1 Primary Polyclonal Antibody
Also known asSUV39H1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSUV39H1
SpecificityThis is a highly specific antibody against SUV39H1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Histone-lysine N-methyltransferase SUV39H1
Gene ID number6839
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen BMP-induced repression, Component of the eNoSC (energy-dependent nucleolar silencing) complex, The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, repression of switch recombination to IgA and regulation of telomere length, such as repression of MYOD1-stimulated differentiation, SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names H3 K9 HMTase1, H3 lysine 9 specic 1, H3-K9-HMTase 1, Histone H3 K9 methylation, Histone H3 Lys 9 methylation, Histone H3-K9 methyltransferase 1, Histone H3-K9 methyltransferase1, Histone lysine N methyltransferase, Histone lysine N methyltransferase H3 lysine 9 specic 1, Histone-lysine N-methyltransferase SUV39H1, KMT1 A, Lysine N methyltransferase 1A, Lysine N-methyltransferase 1A, MG44, Position-effect variegation 3-9 homolog, SUV39 H1, SUV39H, SUV39H1, SUV91_HUMAN, Suppressor of variegation 3 9 homolog 1 Drosophila, Suppressor of variegation 3-9 homolog 1, Suvar3 9 homolog 1, Suvar3-9 homolog 1, mIS6, H3 K9 HMTase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSUV39H1
Short nameSUV39H1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSUV39H1 (Antibody to)
Alternative techniqueantibodies
Identity 11479
Gene SUV39H1
Long gene name suppressor of variegation 3-9 homolog 1
Synonyms gene SUV39H
Synonyms gene name suppressor of variegation 3-9 (Drosophila) homolog 1 suppressor of variegation 3-9 homolog 1 (Drosophila)
Synonyms KMT1A
Locus Xp11, 23
Discovery year 1996-04-12
GenBank acession AF019968
Entrez gene record 6839
Pubmed identfication 10202156
RefSeq identity NM_003173
Classification Lysine methyltransferases
Havana BLAST/BLAT OTTHUMG00000022701
Locus Specific Databases Mental Retardation database

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