Name : SUV39H1 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9991022318
| Long name | ALEXA FLUOR 555 Conjugated, SUV39H1 Polyclonal Antibody |
| Also known as | Anti-SUV39H1 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SUV39H1 |
| Specificity | This is a highly specific antibody against SUV39H1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Histone-lysine N-methyltransferase SUV39H1 |
| Gene ID Number | 6839 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | BMP-induced repression, Component of the eNoSC (energy-dependent nucleolar silencing) complex, The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, repression of switch recombination to IgA and regulation of telomere length, such as repression of MYOD1-stimulated differentiation, SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | KMT1A |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | SUV39H1 |
| Short name | SUV39H1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, SUV39H1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11479 |
| Gene | SUV39H1 |
| Long gene name | suppressor of variegation 3-9 homolog 1 |
| Synonyms gene | SUV39H |
| Synonyms gene name | suppressor of variegation 3-9 (Drosophila) homolog 1 suppressor of variegation 3-9 homolog 1 (Drosophila) |
| Locus | Xp11, 23 |
| Discovery year | 1996-04-12 |
| GenBank acession | AF019968 |
| Entrez gene record | 6839 |
| Pubmed identfication | 10202156 |
| RefSeq identity | NM_003173 |
| Classification | Lysine methyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000022701 |
| Locus Specific Databases | Mental Retardation database |