Name : SUV39H1 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6584171714
| Long name | ALEXA FLUOR 647 Conjugated, SUV39H1 Polyclonal Antibody |
| Also known as | Anti-SUV39H1 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SUV39H1 |
| Specificity | This is a highly specific antibody against SUV39H1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Histone-lysine N-methyltransferase SUV39H1 |
| Gene ID Number | 6839 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | BMP-induced repression, Component of the eNoSC (energy-dependent nucleolar silencing) complex, The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, repression of switch recombination to IgA and regulation of telomere length, such as repression of MYOD1-stimulated differentiation, SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | KMT1A |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the SUV39H1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | SUV39H1 |
| Short name | SUV39H1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, SUV39H1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11479 |
| Gene | SUV39H1 |
| Long gene name | suppressor of variegation 3-9 homolog 1 |
| Synonyms gene | SUV39H |
| Synonyms gene name | suppressor of variegation 3-9 (Drosophila) homolog 1 suppressor of variegation 3-9 homolog 1 (Drosophila) |
| Locus | Xp11, 23 |
| Discovery year | 1996-04-12 |
| GenBank acession | AF019968 |
| Entrez gene record | 6839 |
| Pubmed identfication | 10202156 |
| RefSeq identity | NM_003173 |
| Classification | Lysine methyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000022701 |
| Locus Specific Databases | Mental Retardation database |