Name : SUV39H1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6024024963
| Long name | FITC Conjugated, SUV39H1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | SUV39H1 |
| Specificity | This is a highly specific antibody against SUV39H1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human Histone-lysine N-methyltransferase SUV39H1 |
| Gene ID number | 6839 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | BMP-induced repression, Component of the eNoSC (energy-dependent nucleolar silencing) complex, The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, repression of switch recombination to IgA and regulation of telomere length, such as repression of MYOD1-stimulated differentiation, SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | KMT1A |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | SUV39H1 Conjugated |
| Short name | FITC Conjugated, SUV39H1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, SUV39H1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11479 |
| Gene | SUV39H1 |
| Long gene name | suppressor of variegation 3-9 homolog 1 |
| Synonyms gene | SUV39H |
| Synonyms gene name | suppressor of variegation 3-9 (Drosophila) homolog 1 suppressor of variegation 3-9 homolog 1 (Drosophila) |
| Locus | Xp11, 23 |
| Discovery year | 1996-04-12 |
| GenBank acession | AF019968 |
| Entrez gene record | 6839 |
| Pubmed identfication | 10202156 |
| RefSeq identity | NM_003173 |
| Classification | Lysine methyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000022701 |
| Locus Specific Databases | Mental Retardation database |