Name : SUZ12 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN5705416923
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | SUZ12 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the SUZ12 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This SUZ12 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q15022 |
| Purity | Antigen affinity |
| Description | Component of the PRC2/EED-EZH2 complex, Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A, The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, leading to transcriptional repression of the affected target gene, thereby linking two epigenetic repression systems, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, Polycomb group (PcG) protein |
| Immunogen | A portion of amino acids 559-588 from the human protein was used as the immunogen for this SUZ12 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the SUZ12 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | SUZ12 |
| Short name | SUZ12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | SUZ12 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17101 |
| Gene | SUZ12 |
| Long gene name | SUZ12 polycomb repressive complex 2 subunit |
| Synonyms gene name | suppressor of zeste 12 homolog (Drosophila) |
| Synonyms | JJAZ1 KIAA0160 CHET9 |
| Locus | 17q11, 2 |
| Discovery year | 2004-12-14 |
| GenBank acession | D63881 |
| Entrez gene record | 23512 |
| Pubmed identfication | 8590280 11371647 18784248 |
| RefSeq identity | NM_015355 |
| Classification | Polycomb repressive complex 2 Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000132813 |