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SV2C Antibody, FITC Conjugated

SV2C Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, SV2C Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSV2C
SpecificityThis is a highly specific antibody against SV2C
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human SV2C
Gene ID number22987
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background SV2 proteins are abundant, SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, SV2A and SV2B, SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates, SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation, SV2A is abundantly expressed in the subcortex, SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex, SV2C, and also in most neuroendocrine secretory granules, and one minor isoform, hydrophobic, independent of transmitter type, membrane glycoproteins that are expressed as two major isoforms, specifically in the synaptic vesicles of all presynaptic nerve terminals, In all vertebrates
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSV2C Conjugated
Short name FITC Conjugated, SV2C Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, SV2C (Antibody to)
Alternative techniqueantibodies
Identity 30670
Gene SV2C
Long gene name synaptic vesicle glycoprotein 2C
Locus 5q13, 3
Discovery year 2004-04-01
GenBank acession AB028977
Entrez gene record 22987
Pubmed identfication 10470851 9801366
Havana BLAST/BLAT OTTHUMG00000162384

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