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Synaptic Ras-GAP 1 Antibody

Synaptic Ras-GAP 1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSynaptic Ras-GAP 1 Primary Polyclonal Antibody
Also known asSynaptic Ras-GAP 1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSynGAP
SpecificityThis is a highly specific antibody against SynGAP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Synaptic Ras-GAP 1/SynGAP
Gene ID number8831
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors, Its activity is inhibited by phosphorylation by CaMKII, SynGAP (for synaptic GTPase activating protein), SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins, SynGAP may be involved in the regulation of BDNF as well as Ras signaling, a novel synaptic RasGAP, are involved in the organization of synaptic structure, hippocampus and olfactory bulb, is a brain-specific protein abundant in the cortex, which are known to bind to and cluster various membrane proteins, which could result in the activation of the MAP kinase pathway, The PSD-95/SAP 90 family of proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DKFZp761G1421, KIAA1938, MRD5, OTTHUMP00000064825, RASA 1, RASA 5, RASA1, RASA5, Ras GTPase activating protein SynGAP, Ras GTPase-activating protein SynGAP, SYGP1_HUMAN, SYNGAP 1, SYNGAP1, SYNGAP1, Synaptic Ras GAP 1, Synaptic Ras GTPase activating protein 1, Synaptic Ras GTPase activating protein 1 homolog, Synaptic Ras GTPase activating protein 135kDa, Synaptic Ras GTPase-activating protein 1, Synaptic Ras-GAP 1, p135 SynGAP, synaptic Ras GTPase activating protein, Neuronal RasGAP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSynaptic Ras-GAP 1
Short nameSynaptic Ras-GAP 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSynaptic Ras-GAP 1 (Antibody to)
Alternative techniqueantibodies
Identity 9871
Gene RASA1
Long gene name RAS p21 protein activator 1
Synonyms gene RASA
Synonyms gene name RAS p21 protein activator (GTPase activating protein) 1
Synonyms GAP CM-AVM p120GAP p120RASGAP p120
Synonyms name capillary malformation-arteriovenous malformation p120 RAS GTPase activating protein
Locus 5q14, 3
Discovery year 1989-06-30
Entrez gene record 5921
Pubmed identfication 15917201
RefSeq identity NM_002890
Classification Pleckstrin homology domain containing SH2 domain containing C2 and RasGAP domain containing
Havana BLAST/BLAT OTTHUMG00000162605
Locus Specific Databases SH2base: Database for pathogenic SH2 domain mutations

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