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Synaptic Ras-GAP 1 Antibody, Cy5 Conjugated

Synaptic Ras-GAP 1 Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, Synaptic Ras-GAP 1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenSynGAP
SpecificityThis is a highly specific antibody against SynGAP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Synaptic Ras-GAP 1/SynGAP
Gene ID number8831
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors, Its activity is inhibited by phosphorylation by CaMKII, SynGAP (for synaptic GTPase activating protein), SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins, SynGAP may be involved in the regulation of BDNF as well as Ras signaling, a novel synaptic RasGAP, are involved in the organization of synaptic structure, hippocampus and olfactory bulb, is a brain-specific protein abundant in the cortex, which are known to bind to and cluster various membrane proteins, which could result in the activation of the MAP kinase pathway, The PSD-95/SAP 90 family of proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms GAP CM-AVM p120GAP p120RASGAP p120
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetSynaptic Ras-GAP 1 Conjugated
Short name Conjugated, Synaptic Ras-GAP 1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, Synaptic Ras-GAP 1 (Antibody to)
Alternative techniqueantibodies
Identity 9871
Gene RASA1
Long gene name RAS p21 protein activator 1
Synonyms gene RASA
Synonyms gene name RAS p21 protein activator (GTPase activating protein) 1
Synonyms name capillary malformation-arteriovenous malformation p120 RAS GTPase activating protein
Locus 5q14, 3
Discovery year 1989-06-30
Entrez gene record 5921
Pubmed identfication 15917201
RefSeq identity NM_002890
Classification Pleckstrin homology domain containing SH2 domain containing C2 and RasGAP domain containing
Havana BLAST/BLAT OTTHUMG00000162605
Locus Specific Databases SH2base: Database for pathogenic SH2 domain mutations

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