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SYVN1 Antibody

SYVN1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSYVN1 Primary Polyclonal Antibody
Also known asSYVN1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSYVN1
SpecificityThis is a highly specific antibody against SYVN1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range570-610/617
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SYVN1
Gene ID number84447
Swiss ProtQ86TM6
Tested Applications IF(IHC-F), IF(IHC-P), IHC-F, IHC-P, WB
Recommended dilutions IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200), IHC-F(1:100-500), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also promotes the degradation of normal but naturally short-lived proteins such as SGK, Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins, Protects cells from ER stress-induced apoptosis, Protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation, Sequesters p53/TP53 in the cytoplasm and promotes its degradation, cell cycle regulation and apoptosis, promoting their degradation, thereby negatively regulating its biological function in transcription, Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names E3 ubiquitin-protein ligase synoviolin, HRD1, KIAA181, SYVN1, Synovial apoptosis inhibitor 1, DER3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSYVN1
Short nameSYVN1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name synoviolin (Antibody to), synovial apoptosis inhibitor 1
Alternative techniqueantibodies
Alternative to gene target BT, SYVN1 and IDBG-56611 and ENSG00000162298 and 102465449, Syvn1 and IDBG-134090 and ENSMUSG00000024807 and 74126, metal ion binding, nuclei, synoviolin, this GO :0001701 and in utero embryonic development and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016881 and acid-amino acid ligase activity and molecular function this GO :0018279 and protein N-linked glycosylation via asparagine and biological process this GO :0030433 and ER-associated ubiquitin-dependent protein catabolic process and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0046872 and metal ion binding and molecular function this GO :1902236 and negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016881: acid-amino acid ligase activity and also this GO :0046872: metal ion binding, this GO :0008270: zinc ion binding, this GO :0016881: acid-amino acid ligase activity, this GO :0046872: metal ion binding, 54995 and IDBG-644142 and ENSBTAG00000005076 and 508358, 84447, synovial apoptosis inhibitor 1
Identity 20738
Gene SYVN1
Long gene name synoviolin 1
Synonyms gene name synovial apoptosis inhibitor 1, synoviolin
Synonyms HRD1 DER3
Synonyms name HMG-coA reductase degradation 1 homolog (S, cerevisiae)
Locus 11q13, 1
Discovery year 2004-07-28
GenBank acession AB085847
Entrez gene record 84447
Pubmed identfication 12975321
RefSeq identity NM_032431
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000165607

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