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TAK1 Antibody, ALEXA FLUOR 555

TAK1 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, TAK1 Polyclonal Antibody
Also known asAnti-TAK1 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTAK1
SpecificityThis is a highly specific antibody against TAK1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range560-600/606
Subcellular location Cell membrane, Cytoplasm
SourceKLH conjugated This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAP3K7/TAK1
Gene ID Number6885
Swiss ProtO43318
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), Ceramides are also able to activate MAP3K7/TAK1, In osmotic stress signaling, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7, MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis, Mediates signal transduction of TRAF6, Once activated, Plays an important role in the cascades of cellular responses evoked by changes in the environment, Promotes TRIM5 capsid-specific restriction activity, TGFB-related factors like BMP2 and BMP4, These MAP2Ks in turn activate p38 MAPKs, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, but not that of NF-kappa-B, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK), plays a major role in the activation of MAPK8/JNK1, toll-like receptors (TLR), transforming growth factor-beta (TGFB), tumor necrosis factor receptor CD40 and B-cell receptor (BCR), various cytokines including interleukin-1 (IL-1), while nuclear factor-kappa B is activated by IKK, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms MEKK7
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetTAK1
Short nameTAK1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, TAK1 (Antibody to)
Alternative techniqueantibodies
Identity 6859
Gene MAP3K7
Long gene name mitogen-activated protein kinase kinase kinase 7
Synonyms gene TAK1
Synonyms name TGF-beta activated kinase 1
Locus 6q15
Discovery year 1998-05-22
GenBank acession AB009356
Entrez gene record 6885
Pubmed identfication 9466656
RefSeq identity NM_145331
Classification Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT OTTHUMG00000015217
Locus Specific Databases The Globin Gene Server

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