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TAK1(Ser192) Antibody

TAK1(Ser192) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTAK1(Ser192) Primary Polyclonal Antibody
Also known asTAK1(Ser192) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTAK1 Ser192
SpecificityThis is a highly specific antibody against TAK1 Ser192
Modification(s)Phosphorylation
Modification site(s)Ser192
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human TAK1 around the phosphorylation site of Ser192
Gene ID number7182
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen TAB1 and TAB2 are TAK1 binding proteins that may function as activators of the TAK1 (TGF b activated kinase 1) MAPKKK in TGF b signal transduction, TAB1 induced TAK1 activation promoted the dissociation of active forms of IKKa and IKK b from active TAK1, TAK1 is stimulated in response to TGF beta and bone morphogenetic protein, TAK1 was suggested to act as a regulatory kinase of IKKs, TNF a activated endogenous TAK1, These results suggest that TAK1 functions as a mediator in the signaling pathway of TGF beta superfamily members, and the kinase negative TAK1 acted as a dominant negative inhibitor against TNF a induced NFkB activation, whereas the IKK mutants remained to interact with active TAK1, TAK1 (or MAP3K7) was shown to participate in regulation of transcription by transforming growth factor beta (TGF beta)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names M3K7_HUMAN, MAP3K 7, MEKK7, Map3k7, Mitogen activated protein kinase kinase kinase 7, Mitogen-activated protein kinase kinase kinase 7, Mitogen-activated protein kinase kinase kinase 7, TAK1, TGF beta activated kinase 1, TGF-beta-activated kinase 1, TGF1a, Transforming growth factor beta activated kinase 1, Transforming growth factor-beta-activated kinase 1, MAP3K7phospho S192
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTAK1(Ser192)
Short nameTAK1(Ser192) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTAK1(Ser192) (Antibody to)
Alternative techniqueantibodies
Identity 6859
Gene MAP3K7
Long gene name mitogen-activated protein kinase kinase kinase 7
Synonyms gene TAK1
Synonyms MEKK7
Synonyms name TGF-beta activated kinase 1
Locus 6q15
Discovery year 1998-05-22
GenBank acession AB009356
Entrez gene record 6885
Pubmed identfication 9466656
RefSeq identity NM_145331
Classification Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT OTTHUMG00000015217
Locus Specific Databases The Globin Gene Server

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