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TAK1(Ser412) Antibody, Cy7 Conjugated

TAK1(Ser412) Antibody, Cy7 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, TAK1(Ser412) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTAK1 Ser412
SpecificityThis is a highly specific antibody against TAK1 Ser412
ModificationPhosphorylation
Modification siteSer412
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from mouse TAK1 around the phosphorylation site of Ser412
Gene ID number26409
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background TAB1 and TAB2 are TAK1 binding proteins that may function as activators of the TAK1 (TGF b activated kinase 1) MAPKKK in TGF b signal transduction, TAB1 induced TAK1 activation promoted the dissociation of active forms of IKKa and IKK b from active TAK1, TAK1 is stimulated in response to TGF beta and bone morphogenetic protein, TAK1 was suggested to act as a regulatory kinase of IKKs, TNF a activated endogenous TAK1, These results suggest that TAK1 functions as a mediator in the signaling pathway of TGF beta superfamily members, and the kinase negative TAK1 acted as a dominant negative inhibitor against TNF a induced NFkB activation, whereas the IKK mutants remained to interact with active TAK1, TAK1 (or MAP3K7) was shown to participate in regulation of transcription by transforming growth factor beta (TGF beta)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms MEKK7
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetTAK1(Ser412) Conjugated
Short name Conjugated, TAK1(Ser412) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, TAK1(Ser412) (Antibody to)
Alternative techniqueantibodies
Identity 6859
Gene MAP3K7
Long gene name mitogen-activated protein kinase kinase kinase 7
Synonyms gene TAK1
Synonyms name TGF-beta activated kinase 1
Locus 6q15
Discovery year 1998-05-22
GenBank acession AB009356
Entrez gene record 6885
Pubmed identfication 9466656
RefSeq identity NM_145331
Classification Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT OTTHUMG00000015217
Locus Specific Databases The Globin Gene Server

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