Name : Talin 2 Antibody / TLN2
Supplier : NJS POLY
Price :406
SKU : GEN8316378194
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Talin 2 / TLN2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (FFPE): 0, Western blot: 0 |
| Notes | Optimal dilution of the Talin 2 antibody should be determined by the researcher |
| Intented use | This Talin 2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9Y4G6 |
| Purity | Antigen affinity |
| Description | It belongs to the talin protein family, Talin-2 is expressed at high levels in cardiac muscle and functions to provide linkages between the extracellular matrix and actin cytoskeleton at costamere structures to transduce force laterally, This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts, Talin 2 is a protein in humans that is encoded by the TLN2 gene |
| Immunogen | Amino acids NPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEV were used as the immunogen for the Talin 2 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Talin 2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | membranous, Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Talin 2 / TLN2 |
| Short name | Talin 2 Antibody / TLN2 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Talin 2 (Antibody to) / talin 2 |
| Alternative technique | antibodies |
| Alternative to gene target | Cell surfaces, TLN2 and IDBG-15260 and ENSG00000171914 and 83660, TLN2 and IDBG-646546 and ENSBTAG00000003667 and 528252, Tln2 and IDBG-180368 and ENSMUSG00000052698 and 70549, actin filament binding, this GO :0001726 and ruffle and cellular component this GO :0003779 and actin binding and molecular function this GO :0005158 and insulin receptor binding and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005200 and structural constituent of cytoskeleton and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005916 and fascia adherens and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0007016 and cytoskeletal anchoring at plasma membrane and biological process this GO :0007043 and cell-cell junction assembly and biological process this GO :0007155 and cell adhesion and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0045202 and synapse and cellular component this GO :0051015 and actin filament binding and molecular function, this GO :0003779: actin binding, this GO :0003779: actin binding and also this GO :0005158: insulin receptor binding and also this GO :0005198: structural molecule activity and also this GO :0005200: structural constituent of cytoskeleton and also this GO :0005515: protein binding and also this GO :0051015: actin filament binding, this GO :0005158: insulin receptor binding, this GO :0005198: structural molecule activity, this GO :0005200: structural constituent of cytoskeleton, this GO :0005515: protein binding, this GO :0051015: actin filament binding, talin 2 |
| Identity | 15447 |
| Gene | TLN2 |
| Long gene name | talin 2 |
| Synonyms | KIAA0320 ILWEQ |
| Locus | 15q22, 2 |
| Discovery year | 2001-04-25 |
| GenBank acession | AB002318 |
| Entrez gene record | 83660 |
| Pubmed identfication | 9205841 11527381 |
| Classification | FERM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000133679 |